Results 81 to 90 of about 98,772 (287)

Introduction - Strong interaction in the nuclear medium: new trends [PDF]

open access: yes, 2009
Introduction lecture of the 2009 International Joliot-Curie School, Lacanau, France. Other lectures available soon at "http://www.cenbg.in2p3.fr/joliot-curie/spip.php?rubrique26&lang=fr"Recent achievements in nuclear forces theory open new perspectives ...
Lacroix, D.
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Steatosis-induced proteins adducts with lipid peroxidation products and nuclear electrophilic stress in hepatocytes

open access: yesRedox Biology, 2015
Accumulating evidence suggests that fatty livers are particularly more susceptible to several pathological conditions, including hepatic inflammation, cirrhosis and liver cancer. However the exact mechanism of such susceptibility is still largely obscure.
Sarit Anavi   +3 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Research Note: Relationships between texture and water property measurements in raw intact broiler breast fillets with the wooden breast condition

open access: yesPoultry Science
: Relationships between texture measurements and meat water properties were investigated in raw intact broiler breast fillets with the wooden breast (WB) condition. Texture measurements included subjective WB scores and blunt Meullenet-Owens Razor Shear (
Bin Pang   +7 more
doaj   +1 more source

Effect of Thermal Annealings and Cooling Methods on Electrophysical Parameters of n Si Doped with Phosphorus Impurity Via the Melt and by Nuclear Transmutation Technique

open access: yesФізика і хімія твердого тіла, 2018
The effect of the different regimes of heat treatment on the kinetics of electronic processes in silicon crystals doped with phosphorus impurity via the melt and by nuclear transmutation technique.
G. P. Gaidar
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Coupling of nanomechanical resonators to controllable quantum systems [PDF]

open access: yes, 2014
The coupling of nanomechanical resonators to controllable quantum systems represents a growing and promising area of research. Recent advances in this field have brought to astonishing results, such as the initialization of a mechanical resonator into ...
Montinaro, Michele
core   +1 more source

Electronic Coherences Built by Ultrashort Pulse Drive the Vibronic Forces at Nonadiabatic Seams

open access: yesUltrafast Science
We show that the quantum force that the electrons in a molecule exert on the nuclei remains local even in the presence of strong nonadiabatic interactions.
Gaurav Pandey   +3 more
doaj   +1 more source

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