Results 91 to 100 of about 1,185,468 (303)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The geodetic domination number for the product of graphs [PDF]
A subset S of vertices in a graph G is called a geodetic set if every vertex not in S lies on a shortest path between two vertices from S. A subset D of vertices in G is called dominating set if every vertex not in D has at least one neighbor in D.
S. Robinson Chellathurai +1 more
doaj
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Product Differentiation, Cost-Reducing Mergers, and Consumer Welfare [PDF]
Cost synergies are an explicitly recognized justification for a two-firm merger and empirical techniques are now widely used to assess the impact of cost-reducing mergers on prices and welfare in the postmerger market.
George Norman +2 more
core
Closed Formulae for the Strong Metric Dimension of Lexicographic Product Graphs
Given a connected graph G, a vertex w ∈ V (G) strongly resolves two vertices u, v ∈ V (G) if there exists some shortest u − w path containing v or some shortest v − w path containing u. A set S of vertices is a strong metric generator for G if every pair
Kuziak Dorota +2 more
doaj +1 more source
On global (strong) defensive alliances in some product graphs
A defensive alliance in a graph is a set $S$ of vertices with the property that every vertex in $S$ has at most one more neighbor outside of $S$ than it has inside of $S$. A defensive alliance $S$ is called global if it forms a dominating set. The
Ismael Gonz\'alez Yero +2 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Determination of fission product yields of 235U using gamma ray spectroscopy
textIt is important to have a method of experimentally calculating fission product yields. Statistical calculations and simulations produce very large uncertainties.
Lu, Christopher Hing
core

