Results 91 to 100 of about 1,125,105 (260)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On the strong metric generators of strong product graphs
, 2013 12 ...
Kuziak, Dorota +2 more
openaire +2 more sources
SUPEREULERIAN OF STRONG PRODUCTS
Far East Journal of Mathematical Sciences (FJMS), 2020 A directed graph (digraph for short) $D$ is called a supereulerian if $D$ contains a spanning eulerian subdigraph. A strong product digraph of $D_1$ and $D_2$ is both of a Cartesian product digraph and weak (tensor) product digraph of $D_1$ and $D_2$. Sufficient conditions on $D_1$ and $D_2$ are obtained for the strong product digraph of $D_1$ and $D_2$
openaire +1 more source
The Restricted Edge-Connectivity of Strong Product Graphs
AxiomsThe restricted edge-connectivity of a connected graph G, denoted by λ′(G), if it exists, is the minimum cardinality of a set of edges whose deletion makes G disconnected, and each component has at least two vertices.
Hazhe Ye, Yingzhi Tian
doaj +1 more source
On Strong Bounds for Trotter and Zeno Product Formulas with Bosonic Applications [PDF]
QuantumThe Trotter product formula and the quantum Zeno effect are both indispensable tools for constructing time-evolutions using experimentally feasible building blocks. In this work, we discuss assumptions under which quantitative bounds can be proven in the
Tim Möbus
doaj +1 more source