Results 131 to 140 of about 1,185,468 (303)

THE PERFORMANCE OF AGRICULTURAL MARKETING COOPERATIVES IN DIFFERENTIATED PRODUCT MARKETS

open access: yes
Cooperatives, product differentiation, agricultural marketing, Agribusiness,
Cotterill, Ronald W.
core  

A Generalization on Product Degree Distance of Strong Product of Graphs

open access: yes, 2018
In this paper, the exact formulae for the generalized product degree distance, reciprocal product degree distance and product degree distance of strong product of a connected graph and the complete multipartite graph with partite sets of sizes m0, m1, · ·
K. Pattabiraman (5758368)
core   +1 more source

ChatGPT, a Product of AI, and its Influences in the Business World

open access: yes, 2023
Specifically the study analyzes how ChatGPT AI is transforming business operations and enhancing customer experience in customer service, e-commerce, healthcare, finance, marketing, and developer business sectors. Using a comprehensive literature review approach.The study explores the implications of ChatGPT AI for businesses, including its potential ...
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Do Corporate Control and Product Market Competition Lead to Stronger Productivity Growth? Evidence from Market-Oriented and Blockholder-Based Governance Regimes

open access: yes
This study investigates the impact of corporate governance and product market competition on total factor productivity growth for two large samples of German and UK firms. In poorly performing UK firms, the presence of strong outside blockholders lead to
Koke, J., Renneboog, L.D.R.
core  

PRODUCT MANAGEMENT AS FIRM CAPABILITY

open access: yes, 2011
Product management as an organizational system has a long history of practice, which predates most modern academic management research. Its activities span the external environment of the firm, while simultaneously spanning across internal functional ...
Roach, David
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

The independence number of the strong product of odd cycles

open access: yes, 1998
The independence number of the strong product C5⊠C7⊠C7 determined by the NISPOC software package is presented. Better lower bounds on the independence numbers for two infinite families of strong products of three odd cycles are ...
Vesel, Aleksander, Ẑerovnik, Janez
core   +1 more source

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