Results 71 to 80 of about 721,982 (267)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Strong solutions to density-dependent incompressible smectic-A liquid crystal equations

Electronic Journal of Differential Equations
In this article we study a density-dependent hydrodynamic system that models smectic-A liquid crystal flow. We establish the existence and uniqueness of local strong solutions provided that the initial density function has a positive lower bound.
Xue Zhang, Xiaopeng Zhao
doaj  

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

The Local Strong and Weak Solutions for a Generalized Novikov Equation

Abstract and Applied Analysis, 2012
The Kato theorem for abstract differential equations is applied to establish the local well-posedness of the strong solution for a nonlinear generalized Novikov equation in space C([0,T),Hs(R))∩C1([0,T),Hs-1(R)) with s>(3/2).
Meng Wu, Yue Zhong
doaj   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Sing-changing solutions for nonlinear problems with strong resonance

Electronic Journal of Differential Equations, 2012
Using critical point theory and index theory, we prove the existence and multiplicity of sign-changing solutions for some elliptic problems with strong resonance at infinity, under weaker conditions than in the references.
Aixia Qian
doaj  

Two Higgs doublet solutions to the strong CP problem

Journal of High Energy Physics
We solve the strong CP problem in a broad class of two Higgs doublet theories that will be probed at the Large Hadron Collider and at future colliders.
Quentin Bonnefoy, Lawrence Hall, Claudio Andrea Manzari, Bea Noether   +3 more
doaj   +1 more source

The Local Strong and Weak Solutions for a Generalized Pseudoparabolic Equation

Abstract and Applied Analysis, 2012
The Cauchy problem for a nonlinear generalized pseudoparabolic equation is investigated. The well-posedness of local strong solutions for the problem is established in the Sobolev space 𝐶([0,𝑇);𝐻𝑠⋂𝐶(𝑅))1([0,𝑇);𝐻𝑠−1(𝑅)) with 𝑠>3/2, while the existence of ...
Nan Li
doaj   +1 more source

Inflationary solution to the strong CP and μ problems

Physics Letters B, 2005
Version to appear in Physics Letters B.
Eyton-Williams, O.J., King, S.F.
openaire   +3 more sources

Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP‐WT‐2001 Protocol in the SIOP‐UK‐CCLG and SIOP‐GPOH Studies (2001–2022)

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić, Rhoikos Furtwängler, Tanzina Chowdhury, Christian Vokuhl, Jenny Wegert, Norbert Graf   +5 more
wiley   +1 more source