Results 31 to 40 of about 56,138 (219)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia.

PLoS Pathogens, 2017
The co-evolution of myxoma virus (MYXV) and the European rabbit occurred independently in Australia and Europe from different progenitor viruses. Although this is the canonical study of the evolution of virulence, whether the genomic and phenotypic ...
Peter J Kerr, Isabella M Cattadori, Matthew B Rogers, Adam Fitch, Adam Geber, June Liu, Derek G Sim, Brian Boag, John-Sebastian Eden, Elodie Ghedin, Andrew F Read, Edward C Holmes   +11 more
doaj   +1 more source

Characterization and improvements of the UV radiometric calibration for the TROPOMI operational ozone profile retrieval algorithm [PDF]

Atmospheric Measurement Techniques
The European Space Agency (ESA) Sentinel-5 Precursor (S5P) is a low Earth orbit polar satellite carrying the single payload instrument TROPOspheric Monitoring Instrument (TROPOMI).
S. Di Pede, S. Di Pede, E. Loots, A. Ludewig, E. van der Plas, E. van Amelrooy, M. van Hoek, M. Sneep, M. ter Linden, A. Keppens, J. P. Veefkind, J. P. Veefkind   +11 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

THE EUROPEAN UNION EXPOSED TO THE RISK OF THE SOVEREIGN DEBT CRISIS. CASE STUDY: SPAIN AND PORTUGAL [PDF]

Strategii Manageriale, 2013
The global economic crisis, intensely debated, started almost six years ago, subjected the EU to new resistance tests because of the macroeconomic imbalances in the Euro Zone, generated by the increase of sovereign debts, especially in the PIIGS ...
Ioana-Iulica, MIHAI
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Paraguay and its commercial integration: MERCOSUR

Población y Desarrollo, 2019
Universidad Nacional de Asunción. Facultad de Ciencias Económicas. San Lorenzo, Paraguay Integrationist ideas arise in the post-colonial era, at the end of the 18th century and during the 19th century, to boost trade and the economy; the newly ...
Clarissa Melina Rodríguez Cañete
doaj   +1 more source

Characterizations of strongly almost convergent sequences in a Hilbert space or in L^p(T)

International Journal of Contemporary Mathematical Sciences, 2007
In this paper, a Cauchy criterion for strong almost convergence is established. We also characterize strongly almost convergent sequences in a Hilbert space or L p (T ) in terms of their Fourier coefficients, where 1 ≤ p ≤∞ .
Chang-Pao Chen, Meng-Kuang Kuo
openaire   +1 more source