Results 31 to 40 of about 53,419 (219)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Characterization and improvements of the UV radiometric calibration for the TROPOMI operational ozone profile retrieval algorithm [PDF]

open access: yesAtmospheric Measurement Techniques
The European Space Agency (ESA) Sentinel-5 Precursor (S5P) is a low Earth orbit polar satellite carrying the single payload instrument TROPOspheric Monitoring Instrument (TROPOMI).
S. Di Pede   +11 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

THE EUROPEAN UNION EXPOSED TO THE RISK OF THE SOVEREIGN DEBT CRISIS. CASE STUDY: SPAIN AND PORTUGAL [PDF]

open access: yesStrategii Manageriale, 2013
The global economic crisis, intensely debated, started almost six years ago, subjected the EU to new resistance tests because of the macroeconomic imbalances in the Euro Zone, generated by the increase of sovereign debts, especially in the PIIGS ...
Ioana-Iulica, MIHAI
doaj  

Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia.

open access: yesPLoS Pathogens, 2017
The co-evolution of myxoma virus (MYXV) and the European rabbit occurred independently in Australia and Europe from different progenitor viruses. Although this is the canonical study of the evolution of virulence, whether the genomic and phenotypic ...
Peter J Kerr   +11 more
doaj   +1 more source

Characterizations of strongly almost convergent sequences in a Hilbert space or in L^p(T)

open access: yesInternational Journal of Contemporary Mathematical Sciences, 2007
In this paper, a Cauchy criterion for strong almost convergence is established. We also characterize strongly almost convergent sequences in a Hilbert space or L p (T ) in terms of their Fourier coefficients, where 1 ≤ p ≤∞ .
Chang-Pao Chen, Meng-Kuang Kuo
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Paraguay and its commercial integration: MERCOSUR

open access: yesPoblación y Desarrollo, 2019
Universidad Nacional de Asunción. Facultad de Ciencias Económicas. San Lorenzo, Paraguay Integrationist ideas arise in the post-colonial era, at the end of the 18th century and during the 19th century, to boost trade and the economy; the newly ...
Clarissa Melina Rodríguez Cañete
doaj   +1 more source

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