Results 81 to 90 of about 327 (176)
A parallel algorithm for computing Steiner trees in strongly chordal graphs
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openaire +2 more sources
YAP1 mediates tubular cell senescence and drives maladaptive repair following AKI, promoting the AKI to CKD transition. Single‐cell RNA‐seq reveals sustained YAP1 overexpression, fibroblast activation, and pro‐fibrotic tubular cell shift. Senolytic agents or verteporfin (YAP1/TEAD1 inhibitor) suppress YAP1 activity, reduce renal senescence, alleviate ...
Zhibo Zhao +7 more
wiley +1 more source
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu +11 more
wiley +1 more source
Abstract INTRODUCTION Mild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD), shows pronounced clinical heterogeneity poorly explained by pathology burden, representing a gap complicating prognosis. As the brain operates as a complex network for information integration, we hypothesized that connectome architecture mediates the ...
Yating Li +16 more
wiley +1 more source
ChoCo: a Chord Corpus and a Data Transformation Workflow for Musical Harmony Knowledge Graphs. [PDF]
de Berardinis J +3 more
europepmc +1 more source
Chlorella vulgaris biorefineries: sustainable biofuels and high‐value carbon capture
Abstract Global reliance on fossil fuels has created urgent economic and environmental challenges, yet large‐scale use of algal biomass remains limited by production costs. Industrial scaling is constrained by inefficient harvesting and the technical challenges of processing recalcitrant cell walls.
Sandyelle Ferreira Alcântara Araújo +13 more
wiley +1 more source
Using 18S rDNA metabarcoding of stomach contents from two Antarctic nototheniid fishes, we detected 242 parasite OTUs. Protists dominated diversity, metazoans dominated abundance, and depth structured assemblages. Novel parasite–host associations and previously unreported pathogenic protists highlight fish metabarcoding as a tool for biodiversity and ...
Micaela B. Ruiz +6 more
wiley +1 more source
Structural and Functional Neuroimaging Findings in Fibromyalgia: A Systematic Review
ABSTRACT Background and Objective Fibromyalgia (FM) is a nociplastic chronic pain syndrome in which neuroimaging indicates central nervous system involvement, yet findings remain inconsistent across methods. We systematically reviewed structural and functional neuroimaging studies in adults with FM to identify the most reproducible cross‐modal ...
Flávio Antônio Duboc Flutt +5 more
wiley +1 more source
Unsupervised clustering of resting‐state fMRI in a large adolescent cohort reveals distinct functional brain subgroups. These subgroups show divergent developmental trajectories and are associated with sociodemographic context, highlighting the role of social environment in shaping adolescent brain development. ABSTRACT Adolescence is a critical period
Jiangyun Hou +4 more
wiley +1 more source

