Results 31 to 40 of about 167,051 (218)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Perceptions and Responses of Diversified Farm Producers in the Northern Great Plains to the Early Stage of the COVID-19 Pandemic

Frontiers in Sustainable Food Systems, 2022
The initial months of the COVID-19 pandemic revealed unique vulnerabilities of the global food system with notable societal consequences, calling for the need to implement resilience strategies to support food security for all.
Roland Ebel, Selena Ahmed, Teresa Warne, Alexandria Moxley, Irene Grimberg, Meghann Jarchow, Fabian D. Menalled   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Teacher Perceptions about the Culturally Responsive Education Approach of the Turkish Education System: Q Methodology Study

Journal of Research in Social Sciences and Language
The aim of this study is to examine which issues teachers' perspectives focus on in culturally responsive educational practices within the Turkish education system, identifying points of consensus and disagreement, and exploring the reasons behind the ...
Osman Barutcu, Gürkan Sarıdaş, Funda Nayir   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A Research on Healthcare Professionals’ Stigma Towards Tuberculosis Patients

Thoracic Research and Practice
OBJECTIVE: Strong collaboration between healthcare professionals and patients is necessary for the control of tuberculosis (TB), a potentially fatal and contagious disease without treatment.
Mehmet Sinan Bodur, Barış Çil
doaj   +1 more source

Too much or too little step width variability is associated with a fall history in older persons who walk at or near normal gait speed

Journal of NeuroEngineering and Rehabilitation, 2005
Background Decreased gait speed and increased stride time, stride length, double support time, and stance time variability have consistently been associated with falling whereas step width variability has not been strongly related to falls.
Newman Anne B, VanSwearingen Jessie M, Berlin Jaime E, Brach Jennifer S, Studenski Stephanie A   +4 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

A systematic analysis of machine learning methods for rock wettability prediction: Algorithm performance and computational considerations

Applied Computing and Geosciences
Rock wettability fundamentally controls fluid distribution in porous media and directly impacts enhanced oil recovery applications. Traditional laboratory measurements, while accurate, are time-consuming and provide limited spatial resolution, which ...
Emil von Rosen Vange, Abduljamiu Amao, Theis Solling   +2 more
doaj   +1 more source

Des territoires sans nom peuvent-ils être sans qualité ? Réflexions sur les modifications de la carte administrative chilienne

L'Espace Politique, 2008
During years, democracy in Chile has been criticized for its lack of democratic representativeness. Then in two points of the country, the extreme north on one side (First Region called Tarapacá Region) and the south on the other side (Tenth Region of ...
Anne-Laure Amilhat Szary
doaj   +1 more source