Results 221 to 230 of about 11,180,110 (256)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Microbiome-Inflammation-Mitochondria Coupling in Neurodegeneration and Depression: An Integrative Opinion. [PDF]

Mol Neurobiol
Stefano GB, Esch T.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Harmonic Control of Dynamical Freezing in Programmable Rydberg Atom Arrays

Ghosh R, Sarkar M, Zindorf B, Mukherjee B, Bose S.   +4 more
europepmc   +1 more source

WGM Single-Molecule Validation of pH-Dependent Molecular Energetics at Gold Nanointerfaces: Influence of Buffer Molecules on Glyphosate Ligand Binding. [PDF]

Adv Sci (Weinh)
Perera KMK, Pedireddy S, Subramanian S, Vollmer F.   +3 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Relative Interacting Atomic Energy Analysis of the Anomeric Effect in Cyclic and Acyclic O-C-X Systems. [PDF]

Molecules
Domingo LR, Ríos-Gutiérrez M, Pérez P.   +2 more
europepmc   +1 more source

Ionic, Directional, and Collective Interaction Regimes in Doped B12 Clusters: An IQA Perspective. [PDF]

Inorg Chem
Guevara-Vela JM, Martín Pendás Á, Rocha-Rinza T.   +2 more
europepmc   +1 more source

The need of a 'self-evolving' research platform in tribology. [PDF]

Natl Sci Rev
Dini D.
europepmc   +1 more source

Bridging Programmatic Gap in Post-TB Treatment Prevention: Applying the COM-B Model and Behavior Change Wheel to Improve the Uptake of TB Preventive Therapy. [PDF]

Open Forum Infect Dis
Izudi J, Sekaggya-Wiltshire C, Kerkhoff AD, Cattamanchi A.   +3 more
europepmc   +1 more source