Results 51 to 60 of about 462,824 (274)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Journal of Applied Mathematics, 2003 We consider a mixed problem with Dirichlet and integral conditions for a second-order hyperbolic equation with the Bessel operator. The existence, uniqueness, and continuous dependence of a strongly generalized solution are proved.
Abdelfatah Bouziani
doaj +1 more source
Dynamics of strongly continuous semigroups associated to certain differential equations [PDF]
, 2015 [EN] The purpose of the Ph.D. Thesis "Dynamics of strongly continuous semigroups associated to certain differential equations'' is to analyse, from the point of view of functional analysis, the dynamics of solutions of linear evolution equations.
Aroza Benlloch, Javier
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An abstract nonlocal functional-differential second order evolution problem
Technical Transactions, 2017 The aim of the paper is to prove two theorems on the existence and uniqueness of mild and classical solutions of a semilinear functional-differential evolution second order equation together with nonlocal conditions.
Byszewski Ludwik
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Physical Review Research, 2022 A close connection between antiferromagnetism and superconductivity is at the core of high-temperature superconductivity. Here, we put forward the projected BCS theory for the unification of antiferromagnetism and strongly correlated superconductivity ...
Hyunwoong Kwon, Kwon Park
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Strongly nonlinear second order differential inclusions with generalized boundary conditions
, 2003 In this paper, we study second order differential inclusions in RN with a maximal monotone term and generalized boundary conditions. The nonlinear differential operator need not be necessary homogeneous and incorporates as a special case the one ...
Kourogenis, NC +2 more
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Implementation of an optimal first-order method for strongly convex total variation regularization [PDF]
, 2011 We present a practical implementation of an optimal first-order method, due to Nesterov, for large-scale total variation regularization in tomographic reconstruction, image deblurring, etc.
Jensen, Tobias Lindstrøm; id_orcid +8 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Lie generators for semigroups of transformations in a Polish space
Electronic Journal of Differential Equations, 1993 We characterize completely the infinitesimal generators of semigroups of linear transformations in $C_b(X)$, the bounded real-valued continuous functions on $X$, that are induced by strongly continuous semigroups of continuous transformations in $X$.
J. R. Dorroh, J. W. Neuberger
doaj