Results 51 to 60 of about 2,837,850 (284)

Strongly Involution k-regular nil clean ring

open access: yesNTU Journal of Pure Sciences
This article is about A-rings R, for which every element is a sum of an involution k-regular element and a nilpotent element, which commute with each other. These rings are called strongly involution k-regular nil-clean rings or SIKRNC rings.
Ali Shakir Mahmood   +1 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

The Cayley graph built upon the semigroup of left ideals of a ring

open access: yes上海师范大学学报. 自然科学版, 2014
We investigate the interaction between a ring R and the Cayley graph Cay(L(R)) of the semigroup of left ideals of R,as well as subdigraphs of this graph.Graph theoretic properties of these graphs are investigated,such as transitive closure,girth,radius ...
Aihua Li, Ralph P.Tucci
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

An internal characterisation of strongly regular rings [PDF]

open access: yesBulletin of the Australian Mathematical Society, 1992
We show that a right duo ring R is strongly regular if and only if for each ideal I of R, the coset product of I in the factor ring R/I is the same as their set product.
Huang, Luosheng, Xue, Weimin
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Normal hyperideals in Krasner (m, n)-hyperrings

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2018
Using a new definition, with respect to [21], for normal hyperideals in Krasner (m, n)-hyperrings, we show that the corresponding quotient structures are (m, n)-rings.
Norouzi Morteza   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy