Results 151 to 160 of about 7,396 (254)

Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics

open access: yesAdvanced Intelligent Discovery, EarlyView.
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha   +2 more
wiley   +1 more source

Au(I) Complex With an Abnormal Carbene Ligand Shows Anti‐Kasha Dual Photoluminescence Emission

open access: yesAngewandte Chemie, EarlyView.
Incorporation of an abnormal N‐heterocyclic carbene into a heteroleptic linear Au(I) complex induces anti‐Kasha dual emission responsive to biologically relevant phenyl sulfate. ABSTRACT We report the first photoactive linear Au(I) complex with an abnormal N‐heterocyclic carbene (aNHC) ligand, Au(aIm)(Cz).
Natesan Mannangatti Rajendran   +5 more
wiley   +2 more sources

Biphasic Bone Implants through Hybrid Extrusion Printing of Thermoplastic Poly(lactic-<i>co</i>-glycolic) acid and Strontium-Modified Calcium Phosphate Bone Cement. [PDF]

open access: yesACS Omega
von Witzleben M   +16 more
europepmc   +1 more source

Wet blending of strontium carbonate and hematite particles for preparation of strontium ferrite magnet

open access: yesInternational Journal of the Society of Materials Engineering for Resources, 1993
FUJITA, Toyohisa   +2 more
openaire   +2 more sources

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification

open access: yesAngewandte Chemie, EarlyView.
While cysteine is widely employed as a nucleophilic handle for peptide modification, the electrophilicity of the oxidized form, cystine, is rarely exploited. This study describes a mild, photochemical coupling of sulfinate salts with peptide disulfides.
Joshua M. Hammond   +7 more
wiley   +2 more sources

Mineralization effect of ion-releasing fiber-reinforced composite in teeth with molar-incisor hypomineralization. [PDF]

open access: yesBiomater Investig Dent
Lassila L   +4 more
europepmc   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Microenvironmental Tuning in Isostructural Conjugated Metal–Organic Frameworks for Superior Photocatalytic H2O2 Generation

open access: yesAngewandte Chemie, EarlyView.
Two isostructural conjugated‐MOFs (Fe‐Tp and Mn‐Tp) photocatalysts were engineered with nonequivalent microenvironmental redox tuning for hydrogen peroxide production. The manganese analog engages both the oxygen reduction reaction and the water oxidation reaction while suppressing decomposition, delivering 10 487 µmol g−1 h−1 with an apparent quantum ...
Kayaramkodath Chandran Ranjeesh   +10 more
wiley   +2 more sources

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