Results 21 to 30 of about 82,891 (271)

SEMA4A: An ontology for emergency notification systems accessibility [PDF]

, 2010
This is the post-print version of the final paper published in Expert Systems with Applications. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Aedo Cuevas, Ignacio, Astorga-Paliza, Francisco, Díaz, Paloma, Malizia, Alessio, Onorati, Teresa   +4 more
core   +4 more sources

Perceptions of Alerts Issued by Social Media Platforms in Response to Self-injury Posts Among Latinx Adolescents: Qualitative Analysis

Journal of Medical Internet Research, 2021
BackgroundThere is growing interest in using social media data to detect and address nonsuicidal self-injury (NSSI) among adolescents.
Linnea I Laestadius, Katherine A Craig, Celeste Campos-Castillo   +2 more
doaj   +1 more source

Virtual Extensive Read-Across: A New Open-Access Software for Chemical Read-Across and Its Application to the Carcinogenicity Assessment of Botanicals

Molecules, 2022
Read-across applies the principle of similarity to identify the most similar substances to represent a given target substance in data-poor situations. However, differences between the target and the source substances exist.
Edoardo Luca Viganò, Erika Colombo, Giuseppa Raitano, Alberto Manganaro, Alessio Sommovigo, Jean Lou CM Dorne, Emilio Benfenati   +6 more
doaj   +1 more source

XML Schema-based Minification for Communication of Security Information and Event Management (SIEM) Systems in Cloud Environments [PDF]

, 2014
XML-based communication governs most of today's systems communication, due to its capability of representing complex structural and hierarchical data.
El-Khouly, Mahmoud, Mostafa, Mahmoud, Moussa, Bishoy   +2 more
core   +3 more sources

Identifying chemicals based on receptor binding/bioactivation/mechanistic explanation associated with potential to elicit hepatotoxicity and to support structure activity relationship-based read-across

Current Research in Toxicology, 2023
The liver is the most common target organ in toxicology studies. The development of chemical structural alerts for identifying hepatotoxicity will play an important role in in silico model prediction and help strengthen the identification of analogs used
Shengde Wu, George Daston, Jane Rose, Karen Blackburn, Joan Fisher, Allison Reis, Bastian Selman, Jorge Naciff   +7 more
doaj   +1 more source

Synthesis and structures of O-anthrylmethyl-substituted hexahomotrioxacalix[3]arenes [PDF]

, 2016
O-Alkylation of 7,15,23-tri-tert-butyl-25,26,27-trihydroxy-2,3,10,11,18,19-hexahomo-3,11,19-trioxacalix[3]arene (1H₃) with 9-chloromethylanthracene 5 was carried out under different reaction conditions.
Ikejiri, Yusuke, Jiang, Xue-Kai, Ni, Xi-Long, Redshaw, Carl, Yamato, Takehiko, Zeng, Xi   +5 more
core   +2 more sources

Modeling and insights into the structural characteristics of drug-induced autoimmune diseases

Frontiers in Immunology, 2022
The incidence and complexity of drug-induced autoimmune diseases (DIAD) have been on the rise in recent years, which may lead to serious or fatal consequences. Besides, many environmental and industrial chemicals can also cause DIAD.
Huizhu Guo, Peitao Zhang, Ruiqiu Zhang, Yuqing Hua, Pei Zhang, Xueyan Cui, Xin Huang, Xiao Li, Xiao Li   +8 more
doaj   +1 more source

Using Molecular Initiating Events to Develop a Structural Alert Based Screening Workflow for Nuclear Receptor Ligands Associated with Hepatic Steatosis [PDF]

, 2016
In silico models are essential to the development of integrated alternative methods to identify organ level toxicity and lead towards the replacement of animal testing.
Cronin, Mark, Mellor, Claire, Steinmetz, Fabian   +2 more
core   +2 more sources

Open-source digital technologies for low-cost monitoring of historical constructions [PDF]

, 2017
This paper shows new possibilities of using novel, open-source, low-cost platforms for the structural health monitoring of heritage structures. The objective of the study is to present an assessment of increasingly available open-source digital modeling ...
Basto, Camilo, Chacón Flores, Rolando Antonio, Pelà, Luca   +2 more
core   +2 more sources

In Silico Prediction of Organ Level Toxicity: Linking Chemistry to Adverse Effects [PDF]

, 2017
In silico methods to predict toxicity include the use of (Quantitative) Structure-Activity Relationships ((Q)SARs as well as grouping (category formation) allowing for read-across.
Cronin, M.T.D, Enoch, S.J, Madden, J.C, Mellor, Claire, Przybylak, K, Richarz, A-N   +5 more
core   +1 more source