Results 281 to 290 of about 305,558 (359)

Structure‐Guided Identification and Evaluation of Epalrestat and Ranirestat‐Like Compounds Against Aldose Reductase: Therapeutic Management of Diabetic Neuropathy

ChemistryOpen, EarlyView.
Structure‐based virtual screening of PubChem compounds identifies two novel epalrestat and ranirestat‐like inhibitors with improved affinity and pharmacokinetic profiles targeting aldose reductase. Molecular docking, ADMET filtering, and 500‐ns molecular dynamics simulations confirm the stability and interaction specificity of the candidates ...
Mohd Shahnawaz Khan, Dharmendra Kumar Yadav, Moyad Shahwan, Anas Shamsi   +3 more
wiley   +1 more source

Coal-forming sedimentary model and its control on vertical reservoir heterogeneity of the upper carboniferous Benxi formation in Ordos basin, China. [PDF]

Sci Rep
Zhang Y, Wu C, Li Y, Li J, Feng C, Li B, Wen Z, Liu X.   +7 more
europepmc   +1 more source

Expert perceptions regarding the effectiveness and feasibility of nature‐based solutions for climate change adaptation in a large Mediterranean Basin

People and Nature, EarlyView.
Abstract Floods and droughts are becoming increasingly frequent and intense in the Mediterranean region. Nature‐based solutions (NBS) are being put forward as cost‐effective solutions for climate change adaptation to reduce the impacts of floods and droughts and provide multiple other benefits and ecosystem services.
Raquel Luján Soto, Carolina Boix‐Fayos, Joris de Vente   +2 more
wiley   +1 more source

Features of Karst Paleogeomorphology and Sedimentary Environment of Ordovician Majiagou Formation in Eastern Ordos Basin. [PDF]

ACS Omega
Chen Z, Zhao Z, Gao J, Zhang Y, Xu W, Bai Y, Zhang Y, Lai Y, Wang C.   +8 more
europepmc   +1 more source

Tectonics and Sedimentation of the Meso- to Neoproterozoic Timan-Varanger Belt along the Northeastern Margin of Baltica [PDF]

, 2000
Olovyanishnikov, V. G., Roberts, D., Siedlecka, A.   +2 more
core  

Cryptic Ice Wedge Networks in Holocene Peat, Yukon‐Kuskokwim Delta, Alaska

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT The Yukon‐Kuskokwim Delta (YKD), covering ~75,000 km2 of Alaska's discontinuous permafrost zone, has a historic (1902–2023) mean annual air temperature of ~−1°C and was previously thought to lack ice wedge networks. However, our recent investigations near Bethel, Alaska, revealed numerous near‐surface ice wedges.
Benjamin M. Jones, Mikhail Z. Kanevskiy, Melissa K. Ward Jones, Phillip R. Wilson, Isaiah Ditmer, Benjamin V. Gaglioti, Eric S. Klein, Rodrigo C. Rangel, Kristi L. Wallace, Miriam C. Jones, Matthew J. Wooller, Yuri Shur   +11 more
wiley   +1 more source

Petrographic image classification of complex carbonate rocks from the Brazilian pre-salt using convolutional neural networks. [PDF]

Sci Rep
Basso M, Souza JPDP, Chinelatto GF, Mansini LAA, Vidal AC.   +4 more
europepmc   +1 more source

Lessons learned exploiting a multi‐year large‐scale data set derived from operational quality assessment of mosquito larval treatments in rain catch basins

Pest Management Science, EarlyView.
Results highlight opposite associations between percentages of positive rain catch basins treated with diflubenzuron and Bacillus against mosquito larvae and/or pupae and the intervals between treatments and inspections, and spatial variability in vector control.
Chiara Virgillito, Eleonora Longo, Silvia Paolucci, Martina Micocci, Mattia Manica, Federico Filipponi, Stefano Vettore, Davide Bonetto, Andrea Drago, Simone Martini, Alessandra Della Torre, Beniamino Caputo   +11 more
wiley   +1 more source

Distribution patterns and driving mechanisms of ciliate communities from continental shelf to deep basin of the Northeastern South China Sea. [PDF]

J Plankton Res
Wen S, Cheng Z, Li G, Li K, Tan Y, Liu W.   +5 more
europepmc   +1 more source

Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

Pest Management Science, EarlyView.
Selective editing out of an insect gut protease cleavage site renders a spider‐derived insecticidal peptide active by ingestion by insect pests. Abstract BACKGROUND The toxin peptide U1‐AGTX‐Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.
Breck R. Davis, Alexandra M. Haase, Joseph S. Tourtois, Daniel L. Hulbert, Rachel E. Cornell, Brian T. DeVree, Cadence J. Flohrschutz, Lucille M. Bell, Daniel C. Peck, Trang T. Nguyen, Lin Bao, Robert M. Kennedy, Kyle D. Schneider   +12 more
wiley   +1 more source