Results 61 to 70 of about 317,667 (308)
Advanced Science, EarlyView.Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan +6 more
wiley +1 more source
Contributions to Geophysics and Geodesy, 2018 This study is a contribution to the planning of hydrocarbon exploration program of the Koum sedimentary basin in North Cameroon. 3D modeling of WGM2012 gravity data derived from EGM2008 geopotential model in the Koum basin was used together with existing
Yves SHANDINI +3 more
doaj +1 more source
Coupled Above‐ and Belowground Ecosystem Stability Worldwide
Advanced Science, EarlyView.Are the worlds above and below our feet in sync? This global exploration reveals an entangled fate between above‐ and belowground ecosystem stability. It identifies arid regions as hotspots for this coupling and highlights temperature stability as a vital safeguard for maintaining ecosystem balance across our warming planet.
Zexin Meng +18 more
wiley +1 more source
Two-objective Optimization of Location and Geometric Characteristics of Rockfill Dams at the Taleghan Basin by NSGA-II [PDF]
Environmental Energy and Economic Research, 2018 Among the structural and non-structural methods of flood control, rockfill dams are a kind of detention structures that increase travel time and reduce the maximum instantaneous flood discharge.
Javad Sarvarian +2 more
doaj +1 more source
Deformation of continental crust along a transform boundary, Coast Mountains, British Columbia [PDF]
, 2010 New structural, paleomagnetic, and apatite (U-Th)/He results from the continental margin inboard of the Queen Charlotte fault (~54°N) delineate patterns of brittle faulting linked to transform development since ~50 Ma.
Bogue, Scott W. +4 more
core +1 more source
Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
Advanced Science, EarlyView.While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
Strike-slip structures and hydrocarbon accumulation in complex fault blocks in Subei Basin
Shiyou shiyan dizhi, 2023 The research on basin formation and hydrocarbon generation and accumulation in the Subei Basin was carried out based on structural geometry and kinematic analyses.
Xuming QIU +3 more
doaj +1 more source
Middle Caddoan Period Archaeology in the Upper Sulphur River Basin [PDF]
, 1997 Middle Caddoan period archaeological sites in the upper Sulphur River basin are rare, by contrast with the lower Sulphur River area, and probably the best-known site of this age in the upper part of the basin is the Hurricane Hill site (41HP106).
Perttula, Timothy K.
core +1 more source
Evidence of Quaternary tectonics along Río Grande valley, southern Malargüe fold and thrust belt, Mendoza, Argentina [PDF]
, 2019 The Malargüe fold and thrust belt is developed in the Argentinian Andes between 34° and 37° S, through the tectonic inversion of Upper Triassic and Lower Jurassic depocenters of the Neuquén Basin, with an uplift history since the Cretaceous.
Colavitto, Bruno +4 more
core +1 more source
Advanced Science, EarlyView.This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen +10 more
wiley +1 more source