Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Expression of concern: "A state-of-the-art review on experimental investigation and finite element analysis on structural behaviour of fibre reinforced polymer reinforced concrete beams" [Heliyon 9 (2023) e14225]. [PDF]
europepmc +1 more source
Fracture behaviour and structural integrity of hemp fibre reinforced composites for low load-bearing aerospace applications. [PDF]
Nagaraja S +3 more
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Relation Between Thermal Analysis, Phase Composition and Structure of Polyurethane Adhesives for Application in Wooden Structural Joints. [PDF]
Szumera M +8 more
europepmc +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Cross-sectional study on community pharmacists' behaviours in providing travel health services in Türkiye: a structural equation modelling approach. [PDF]
Arslan M +2 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Formulation-Driven Rational Architectonic Design of Pomelo (<i>Citrus maxima</i>) Peel-Derived Lignocellulosic Fibre-Enriched Chewable Tablets: Spectroscopic and Morphological Characterization of Structure-Function Relationships. [PDF]
Ahmad SA, Wang L, Arshad A.
europepmc +1 more source

