Results 151 to 160 of about 23,423,883 (325)

Indonesian Economic Structure: An Analysis of Temporal Leontief Inverse

open access: yesJurnal Ekonomi Pembangunan: Kajian Masalah Ekonomi dan Pembangunan, 2015
This study aims to analyze the Indonesia economic structure with employing the temporal Leontief inverse which was developed by Sonis and Hewings (1998) on 1975-2005 Indonesia’s input-output tables.
Firmansyah Firmansyah, Shanty Oktavilia
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Navigation-related structural change in the hippocampi of taxi drivers.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2000
E. Maguire   +6 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Estimating Structural Change with Smooth Transition Regressions: an Application to Meat Demand [PDF]

open access: yes
This paper explores the role of structural change in systems of demand equations. Specifically, we adapt the time—varying regression framework of Lin and Teräsvirta (1994), which in turn is related to the dynamic smooth transition models introduced by ...
Balagtas, Joseph V., Holt, Matthew T.
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Editorial: Integrating age structural change into global policy. [PDF]

open access: yesFront Public Health, 2022
Harper S, Howse K, Chan A.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Structural Change and Performance of Grain Marketing Cooperatives [PDF]

open access: yes
The U.S. grain marketing system has undergone many structural changes in the 1980s. In no part of the system has structural change been more far-reaching and extensive than in farmer-owned cooperatives.
Dahl, Reynold P.
core   +1 more source

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