Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Long-Run Structural and Productivity Change in U.S. Agriculture: Effects of Prices and Policies [PDF]
Long-Run Structural and Productivity Change in U.S. Agriculture: Effects of Prices and Policies by Wallace E. Huffman and Robert E. Evenson The paper presents (1) a conceptual framework for structural change when farms may be multiproduct or specialized ...
Robert E. Evenson, Wallace B. Huffman
core
"There just isn't any other option-so we just have to put up with it": mental health in women's cycling and the necessity of structural change. [PDF]
Front Sports Act Living, 2023 Colangelo J +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Regional Integration and Dynamic Adjustments: Evidence from a Gross National Product Function for Canada and the United States [PDF]
We propose an empirical trade model to test for structural change and dynamic effects induced by free trade agreements for the Canadian and US economies.
Chapda Nana, Guy +2 more
core +1 more source
The Atomic Observation of the Structural Change Process in Pt Networks in Air Using Environmental Cell Scanning Transmission Electron Microscopy. [PDF]
Nanomaterials (Basel), 2023 Takeguchi M, Takei T, Mitsuishi K.
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Learning and structural change in macroeconomic data [PDF]
We include learning in a standard equilibrium business cycle model with explicit growth. We use the model to study how the economy's agents could learn in real time about the important trend-changing events of the postwar era in the U.S., such as the ...
James B. Bullard, John Duffy
core
Promoting Evidence-Based Practice: The Influence of Novel Structural Change to Accelerate Translational Rehabilitation. [PDF]
Arch Phys Med Rehabil, 2023 Rafferty M +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source