Results 181 to 190 of about 23,423,883 (325)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Sectoral Structural Change in a Knowledge Economy [PDF]

open access: yes
The sectoral composition of the US economy has shifted dramatically in the recent decades. At the same time, knowledge and information capital has become increasingly important in modern production processes.
Che, Natasha Xingyuan
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Reimagining Perinatal Mental Health: An Expansive Vision For Structural Change. [PDF]

open access: yesHealth Aff (Millwood), 2021
Foster VA   +14 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Employment growth: cyclical movements or structural change? [PDF]

open access: yes
In judging the degree of slack in the economy, policymakers must determine the origin of any increase in the unemployment rate—specifically, how much of it is due to a cyclical slowdown (driven by the broader economy) as opposed to a structural ...
Ellen R. Rissman
core  

A Note on the Structural Change Test in Highly Parameterized Psychometric Models. [PDF]

open access: yesPsychometrika, 2022
Huth KBS   +5 more
europepmc   +1 more source

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