Results 211 to 220 of about 473,834 (321)

Teaching Structure: A Qualitative Evaluation of a Structural Competency Training for Resident Physicians. [PDF]

open access: yesJ Gen Intern Med, 2017
Neff J   +5 more
europepmc   +1 more source

Pyrazine‐Embedded Two‐Dimensional Conjugated Metal‐Organic Framework with Quasi‐Honeycomb Lattice for High‐Capacitance Lithium‐Ion Storage

open access: yesAngewandte Chemie International Edition, Accepted Article.
As a unique class of framework electronic materials, two‐dimensional conjugated metal‐organic frameworks (2D c‐MOFs) exhibit intrinsic porosity, superior electrical conductivity, and abundant active sites. These properties endow them with great potential in electrochemical lithium‐ion storage.
Xiangyu Li   +13 more
wiley   +1 more source

Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A

open access: yesAngewandte Chemie International Edition, EarlyView.
A biosynthesis route for the polymer precursor tulipalin A starting from isoprenyl acetate is proposed. The alkane monooxygenase AlkB catalyzes the chemoselective terminal hydroxylation of isoprenyl acetate. Rational enzyme engineering further increased the activity of the membrane enzyme.
Andrea Nigl   +11 more
wiley   +1 more source

Integrated Chemoenzymatic Synthesis of the mRNA Vaccine Building Block N1‐Methylpseudouridine Triphosphate

open access: yesAngewandte Chemie International Edition, Accepted Article.
Pseudouridine‐5’‐triphosphate (ΨTP) and the N1‐methylated derivative (m1ΨTP) are critical monomer building blocks of the currently used mRNA vaccines, yet efficient methods of their synthesis from readily accessible substrates remain underdeveloped. We herein report notably atom‐economic and high‐yielding biocatalytic route toward ΨTP (83% yield) and ...
Martin Pfeiffer   +4 more
wiley   +1 more source

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