Results 51 to 60 of about 222,541 (341)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Global translation and adaptation of social medicines and structural competencies
Global Public HealthThis commentary on the special issue of Global Public Health on structural competency in global perspective asks: what is specific to the U.S. about structural competency, and what is its utility beyond the U.S., especially in the ‘global south’? Why are
Helena Hansen
doaj +1 more source
From Particularities to Context: Refining Our Thinking on Illness Narratives. [PDF]
, 2017 This paper examines how illness narratives are used in medical education and their implications for clinicians' thinking and care of patients. Ideally, collecting and reading illness narratives can enhance clinicians' sensitivity and contextual thinking.
Le, Annie +2 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The ASK-SEAT: a competency-based assessment scale for students majoring in clinical medicine
BMC Medical Education, 2022 Background To validate a competency-based assessment scale for students majoring in clinical medicine, ASK-SEAT. Students’ competency growth across grade years was also examined for trends and gaps. Methods Questionnaires were distributed online from May
Linxiang Huang +10 more
doaj +1 more source
CAREER MANAGEMENT IN THE MINISTRY FOR ADMINISTRATIVE REFORM AND THE BUREAUCRATIC STATE APPARATUS [PDF]
, 2016 Career management is one part discussion of human resources management. Human resources reform is a crucial element for the effectiveness of the performance of the bureaucracy.
Irawan, Irawan +3 more
core
Athletes' perceptions of coaching effectiveness and athlete-related outcomes in rugby union: An investigation based on the coaching efficacy model [PDF]
, 2008 This study examined the relationships between athletes' perceptions of coaching effectiveness, based on the coaching efficacy model, and their effort, commitment, enjoyment, self-efficacy, and prosocial and antisocial behavior in rugby union ...
Boardley, Ian D +2 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Frontiers in Psychology, 2023 IntroductionTeachers’ inclusive education competency is the key to the successful implementation of inclusive education. Under the background of China’s vigorous development of inclusive education, the influence mechanism of inclusive education ...
Rui Xue +3 more
doaj +1 more source
Video games as meaningful entertainment experiences [PDF]
, 2015 We conducted an experiment to examine individuals’ perceptions of enjoyable and meaningful video games and the game characteristics and dimensions of need satisfaction associated with enjoyment and appreciation.
Bowman, Nicholas David +5 more
core +2 more sources