Results 121 to 130 of about 4,034,259 (329)
Probing crystal structures of dicarbamate phase change materials to inform structural design
, 2023 Samantha L. Piper +7 more
openalex +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Considering Structural Properties of Inter-organizational Network Fragments during Business-IT Alignment [PDF]
, 2008 Value exchange models can be used to reason about possible networked business constellations. Such inter-organizational business settings are determined in most cases solely from a financial point of view, i.e. by assessing the economic sustainability of
Zarvić, N.
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Behavior sensitivities for control augmented structures [PDF]
During the past few years it has been recognized that combining passive structural design methods with active control techniques offers the prospect of being able to find substantially improved designs.
Lust, R. V. +2 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Some consequences of stress range dependent constitutive models in creep [PDF]
, 2010 Studies of the behaviour of structural components at high temperature subject to creep have a long history and their behavioural characteristics, certainly for constant and cyclic load, well established.
Boyle, James
core
A Structural Model of a Multitasking Salesforce: Multidimensional Incentives and Plan Design
, 2021 Minkyung Kim, K. Sudhir, Kosuke Uetake
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
A study of NACA and NASA published information of pertinence in the design of light aircraft [PDF]
, 1970 Three volume report contains NACA/NASA generated literature pertinent to the design of light aircraft. Information covers structural design, propulsion subsystems, landing gear loads, flutter, performance calculation procedures, and high horsepower ...
core +1 more source