Results 21 to 30 of about 2,823,698 (212)
Automated fully-stressed design with NASTRAN [PDF]
, 1976 An automated strength sizing capability is described. The technique determines the distribution of material among the elements of a structural model.
Haggenmacher, G. W., Wallerstein, D. V.
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Origin of the designability of protein structures [PDF]
Physical Review E, 1999 17 pages, 2 ...
Tatsumi, Rie, Chikenji, George
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
On the line structure of designs
Discrete Mathematics, 1991 A \((v,b,r,k,\lambda)\)-design is a pair \((S,\beta)\), where \(S\) is a \(v\)- set, whose elements are called points, and \(\beta\) is a collection of \(b\) \(k\)-subsets of \(S\), called blocks, such that any pair of points is contained in exactly \(\lambda\) blocks. The parameter \(r=\lambda(v-1)/(k- 1)\) denotes the number of blocks through a point.
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Structural fire design of ear strengthened RC beams [PDF]
, 2017 This paper discusses the structural fire design of reinforced concrete beams strengthened in flexure by means of externally applied reinforcement (EAR). It is focusing on the Eurocode approach for fire rating of individual members.
Matthys, Stijn
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source