Results 121 to 130 of about 6,834,354 (294)
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
This research builds upon existing developments of the partially confirmatory approach by introducing predictors and regularizations to two additional parameter matrices: structural and differential coefficients.
Zhang, Yifan, Chen, Jinsong
core +1 more source
PAY SATISFACTION AND ORGANISATIONAL TRUST: AN IMPORTANCE-PERFORMANCE MAP ANALYSIS [PDF]
Journal of Applied Structural Equation Modeling, 2020 Gabriel C. W. Gim, Wen-Sing Cheah
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
, 2022 This chapter presents an overview of the process of structural equation modeling, involving the steps of model specification, model estimation, overall fit evaluation, model respecification, and local fit assessment (including interpreting the parameters
Klarmann, Martineditor +4 more
core
THE IMPACTS OF STRESS, PROJECT-BASED LEARNING ACTIVITIES, AND MOTIVATION ON STUDENTS’ LEARNING
Journal of Applied Structural Equation Modeling, 2022 João Alberto Arantes do Amaral +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
State-of-art on PLS Path Modeling through the available software [PDF]
The purpose of this paper is to present PLS Path Modeling, to describe the various options of LVPLS 1.8 and PLS-Graph 3.0 for carrying out a path model, and to comment the output of both software. PLS-Graph 3.0 is actually based on LVPLS 1.8. As an added
TENENHAUS, Michel +2 more
core
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source