Results 31 to 40 of about 171,451 (234)

Structural equation modeling in epidemiology

Cadernos de Saúde Pública
Structural equation modeling (SEM) is an important statistical tool for evaluating complex relations in several research areas. In epidemiology, the use and discussion of SEM have been limited thus far. This article presents basic principles and concepts
Leila Denise Alves Ferreira Amorim, Rosemeire L. Fiaccone, Carlos Antônio S. T. Santos, Tereza Nadya dos Santos, Lia Terezinha L. P. de Moraes, Nelson F. Oliveira, Silvano O. Barbosa, Darci Neves dos Santos, Letícia Marques dos Santos, Sheila M. A. Matos, Maurício L. Barreto   +10 more
doaj   +2 more sources

THE RECEPTIVENESS OF THE TEUKU UMAR ISLAMIC LEADERSHIP STYLE AMONG INDONESIAN YOUNG LEADERS [PDF]

Journal of Applied Structural Equation Modeling
Drawing on the theory of planned behaviour (TPB), this paper investigates the factors that influence the behavioural intention of young Indonesian leaders to adopt the Teuku Umar Islamic leadership style.
Zainal Putra, Hanudin Amin, Hamdi Harmen, Said Achmad Kabiru Rafiie   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

SHIPPERS’ SWITCHING BEHAVIOR TOWARD GREEN VEHICLES IN LAST-MILE DELIVERY: EVIDENCE FROM A DEVELOPING COUNTRY [PDF]

Journal of Applied Structural Equation Modeling
The present study aims to determine how value perceptions and green trust influence shippers’ intention to switch toward green vehicles for last-mile delivery.
Xuan Cu Le, Tran Hung Nguyen
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Factors influencing online purchase intention of millennials and gen z consumers [PDF]

Journal of Applied Structural Equation Modeling, 2020
This study examines the factors affecting millennials and generation Z’s purchase intention in online shopping. The variables under investigation, namely, impulse purchase orientation, quality orientation, brand orientation, online trust, and online ...
Nasrul Fadhrullah Isa, Sharifah Nurafizah Syed Annuar, Imelda Albert Gisip, Nelson Lajuni   +3 more
doaj  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A MODIFIED UTAUT IN THE CONTEXT OF M-PAYMENT USAGE INTENTION IN MALAYSIA [PDF]

Journal of Applied Structural Equation Modeling, 2021
Kin Leong Tang, Nai Chiek Aik, Wei Lim Choong   +2 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

THE MEDIATING ROLE OF DRINKING MOTIVES ON THE LINK BETWEEN ALCOHOL USE AND PERSONALITY FACTORS [PDF]

Journal of Applied Structural Equation Modeling, 2023
Rachelle Ann A. Beninsig, Hersheys V. Calumpang, Ma. Olivia B. Espedion, Leandro R. De Luna   +3 more
doaj   +1 more source