Results 31 to 40 of about 166,138 (300)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

THE MEDIATING ROLE OF DRINKING MOTIVES ON THE LINK BETWEEN ALCOHOL USE AND PERSONALITY FACTORS [PDF]

open access: yesJournal of Applied Structural Equation Modeling, 2023
Rachelle Ann A. Beninsig   +3 more
doaj   +1 more source

STRATEGIC AND SUSTAINABLE CORPORATE SOCIAL RESPONSIBILITY FOR MICROFINANCE INSTITUTIONS: A STRUCTURAL EQUATION MODELING ANALYSIS [PDF]

open access: yesJournal of Applied Structural Equation Modeling
Microfinance Institutions (MFIs) often grapple with allocating adequate resources toward Corporate Social Responsibility (CSR), despite their crucial societal impact.
Kevin M. Rivera
doaj   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

CONTROL VARIABLES: A REVIEW AND PROPOSED GUIDELINES [PDF]

open access: yesJournal of Applied Structural Equation Modeling
Although the considerable body of research on control variables offers best practice recommendations, there are still shortcomings in their application in published research papers.
Mumtaz Ali Memon   +4 more
doaj   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada   +3 more
wiley   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

Evaluating feature extraction reproducibility across image biomarker standardization initiative‐compliant radiomics platforms using a digital phantom

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The aim of this study was to thoroughly analyze the reproducibility of radiomics feature extraction across three Image Biomarker Standardization Initiative (IBSI)‐compliant platforms using a digital phantom for benchmarking. It uncovers high consistency among common features while also pointing out the necessity for standardization ...
Han‐Back Shin   +5 more
wiley   +1 more source

EDITORIAL – A REVIEW OF THE METHODOLOGICAL MISCONCEPTIONS AND GUIDELINES RELATED TO THE APPLICATION OF STRUCTURAL EQUATION MODELING: A MALAYSIAN SCENARIO [PDF]

open access: yesJournal of Applied Structural Equation Modeling, 2017
Although structural equation modeling (SEM) is a powerful statistical technique, understanding its methodological assumptions before data analyses is essential to attaining more robust results.
Mumtaz Ali Memon   +4 more
doaj  

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