Results 51 to 60 of about 597,238 (273)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Evaluation of municipal e-government readiness using structural equation modelling technique
The Journal for Transdisciplinary Research in Southern Africa, 2018 The evaluation of municipal e-government readiness can provide a useful barometer to understand the critical needs of citizens. In addition, it can help to improve effectiveness of government services and provide a technology industry access to relevant ...
Seena Joseph, Oludayo O. Olugbara
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Structural equation modelling and system dynamic in the detection of power quality events [PDF]
, 2012 The issues of power quality had been discussed since the starting of power system and it will keep on arise from time to time because power quality is important to electricity consumers at all levels of usage.
Azizan, Ashraf Zulfa
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Dataset on social demographic and employee job satisfaction in the Nigerian manufacturing company
Data in Brief, 2018 The dataset on the effects of social demographic on job satisfaction was obtained through self-administered questionnaire. The survey was situated in a Nigerian manufacturing company and the valid ninety two copies of the questionnaire were analyzed by ...
Adewale O. Osibanjo +3 more
doaj +1 more source
The factorial validity and reliability of three versions of the Aggression Questionnaire using Confirmatory Factor Analysis and Exploratory Structural Equation Modelling [PDF]
, 2015 The Aggression Questionnaire (AQ) measures aggression in four domains: Anger, Hostility, Physical Aggression and Verbal Aggression. Moreover, a number of shorter versions of the AQ have emerged.
Harvey, Séamus A. +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FAKTOR-FAKTOR YANG MEMENGARUHI MINAT BELI PANGAN ORGANIK MELALUI SITUS ONLINE
Jurnal Manajemen & Agribisnis, 2017 This study is aimed to explore the factors that can increase the intention to buy and their implications in the design of marketing sites. Theoretical background used in the study is mainly adopted from the Technology Acceptance Model. Five variables are
Hasrini Sari, Aditya Parama Setiaboedhi
doaj +1 more source