Results 41 to 50 of about 16,460 (260)
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Antecedents of customer switching intention in the Ghanaian telecommunications industry [PDF]
Accounting, 2017 The telecommunications industry continues to experience fierce competition due to the growth in subscribers and the rapid development of new technologies in the sector.
Kwame Simpe Ofori +2 more
doaj +1 more source
Heliyon, 2021 Electric cars are relatively in the early stage of acceptance in Malaysia, the purpose of the current research was to determine the factors affecting the adoption of battery electric vehicles in Kuala Lumpur, Malaysia.
Hamed Khazaei, Mohammad Ali Tareq
doaj +1 more source
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Selecting scaling indicators in structural equation models (sems).
Psychological MethodsIt is common practice for psychologists to specify models with latent variables to represent concepts that are difficult to directly measure. Each latent variable needs a scale, and the most popular method of scaling as well as the default in most structural equation modeling (SEM) software uses a scaling or reference indicator.
Bollen, Kenneth A. +2 more
openaire +2 more sources
Indonesian Journal of Business and EntrepreneurshipBackground: This study aimed to fill a critical research gap by comparing traditional Structural Equation Modelling (SEM) with hybrid Bayesian-Machine Learning (ML) models in marketing research, focusing on the limited exploration of these advanced ...
Chacha Magasi
doaj +1 more source
Advanced Engineering Materials, EarlyView.The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi +3 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.This study presents a reversible temperature sensor with high switching ratio, ∼103. The device is fabricated using PET‐ITO and carbon nanotube dispersions in alkane. Considering its application in cold chain logistics, a proof‐of‐concept with LED is showcased. Thus, a temperature drop below the threshold temperature (crystallization temperature of the
Sunil Kumar Behera +8 more
wiley +1 more source
Educational Process: International Journal, 2015 The basic purpose of this study was to examine the relationships between environmental awareness, environmental attitude, curiosity and exploration in highly gifted students with structural equation modelling.
Hakan Saricam, Suleyman Hilmi Sahin
doaj +1 more source