Results 91 to 100 of about 11,099,772 (293)

lavaan.survey: An R Package for Complex Survey Analysis of Structural Equation Models

open access: yesJournal of Statistical Software, 2014
This paper introduces the R package lavaan.survey, a user-friendly interface to design-based complex survey analysis of structural equation models (SEMs). By leveraging existing code in the lavaan and survey packages, the lavaan.survey package allows for
Daniel Oberski
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Likelihood-preserving normalization in multiple equation models [PDF]

open access: yes
Causal analysis in multiple equation models often revolves around the evaluation of the effects of an exogenous shift in a structural equation.
Tao Zha, Daniel F. Waggoner
core  

Extending Structural Equation Models of Generalizability Theory

open access: yes, 2022
R syntax to replicate analyses in the article: How to Estimate Absolute-Error Components in Structural Equation Models of Generalizability ...
Terrence D. Jorgensen
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Structural equation models ‐ standardized coefficients.

open access: yes
Structural equation models ‐ standardized coefficients.
Antonio Villarroel-Villarroel (12908497)   +3 more
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

The Asymptotic distribution of the LIML Estimator in a Partially Identified Structural Equation [PDF]

open access: yes
We derive general formulae for the asymptotic distribution of the LIML estimator for the coefficients of both endogenous and exogenous variables in a partially identified linear structural equation.
Giovanni Forchini
core  

On the Use of Formative Measurement Specifications in Structural Equation Modeling: A Monte Carlo Simulation Study to Compare Covariance-Based and Partial Least Squares Model Estimation Methodologies [PDF]

open access: yes
The broader goal of this paper is to provide social researchers with some analytical guidelines when investigating structural equation models (SEM) with predominantly a formative specification. This research is the first to investigate the robustness and
Ringle, Christian M.   +3 more
core   +2 more sources

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