Results 131 to 140 of about 11,099,772 (293)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Structural parameters under partial least squares and covariance-based structural equation modeling : a comment on Yuan and Deng (2021)

, 2023
In their article, Yuan and Deng argue that a structural parameter under partial least squares structural equation modeling (PLS-SEM) is zero if and only if the same structural parameter is zero under covariance-based structural equation modeling (CB-SEM).
Henseler, Jorg, Kline, Rex B., Rosseel, YvesPP018010009749090000-0002-4129-4477F4D626CE-F0ED-11E1-A9DE-61C894A0A6B4, Trinchera, Laura, Schuberth, Florian, Ronkko, Mikko   +5 more
core  

Structural Equation Modeling Semiparametric Truncated Spline in Banking Credit Risk Behavior Models

Cauchy: Jurnal Matematika Murni dan Aplikasi
Housing is one of the primary needs for every individual. Along with the increasing population growth in Indonesia, the need for housing has also experienced a significant surge.
Devi Veda Amanda, Atiek Iriany, Adji Achmad Rinaldo Fernandes, Solimun Solimun   +3 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Commentary: Structural equation models and causal claims in soil science and biogeochemistry – An equation-free “how to”

Geoderma
Structural equation modeling (SEM) is a set of approaches that have seen exponential usage in the soil sciences as well as the related fields of agriculture and biogeochemistry. When correctly used and interpreted, SEM can be a powerful and flexible tool
Jordon Wade, Teal M. Potter, Andrew J. Margenot   +2 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Conditional inference for possibly unidentified structural equations [PDF]

The possibility that a structural equation may not be identified casts doubt on the measures of estimator precision that are normally used. We argue that the observed identifiability test statistic is directly relevant to the precision with which the ...
Forchini, G., Hillier, G.H.
core  

Bridging the gaps: Comparing structural equation models to network analysis models of depression, anxiety, and perfectionism

International Journal of Personality Psychology
Network models of psychopathology can identify specific items/symptoms that explain the connections among broader constructs such as depression, anxiety, and perfectionism. In two studies, we examine the dynamic interplay between depression, anxiety, and
Andy J. Kim, Sean P. Mackinnon
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source