Results 161 to 170 of about 220,958 (353)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
The Role and Significance of EU Funds for the Republic of Croatia
Ekonomski Vjesnik, 2013 The Republic of Croatia was granted the official candidate country status for the membership in the European Union on 18 June 2004. Thus it gained the opportunity to use pre-accession funds aimed at helping the candidates to bring their institutions and ...
Marija Tolušić +2 more
doaj
European Structural and Investment Funds (ESIFs) and Regional Development across the European Union (EU) [PDF]
Nikolitsa Spilioti +1 more
openalex +1 more source
The role of fiscal transfers for regional economic convergence in Europe [PDF]
This paper provides evidence on the role of net fiscal transfers to households and EU structural funds for per-capita output convergence across a large sample of European regions during the period 1995-2005.
Checherita-Westphal, Cristina +2 more
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
How does Institutional Setting Affect the Impact of EU Structural Funds on Economic Cohesion? New Evidence from Central and Eastern Europe [PDF]
, 2011 Structural Funds are the main instrument of the EU cohesion policy. Their effective use is subject to an ongoing debate in political and scientific circles.
Gruševaja, Marina, Pusch, Toralf
core
Problems of Romanian SMEs with tapping EU structural funds [PDF]
Eastern Journal of European Studies, 2011 Romanian SMEs can directly benefit from the Sectoral Operational Programme “Increase of Economic Competitiveness” (SOP IEC) and some parts of the Regional Operational Programme (ROP) in the 2007–2013 period. There has been wide interest for these subsidies on behalf of SMEs but major problems emerged with the implementation of projects.
openaire +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source