ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
Mechanistic study on the sulfate migration in glycosaminoglycans during MS fragmentation. [PDF]
Polewski L +4 more
europepmc +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Rare Earth Fluorescent Composite Hydrogel with Controllable Color Photoluminescence for Information Encryption. [PDF]
Du J, Zhang D, Zhou T, Diao K, Lei Z.
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Adsorption-Driven Symmetry Lowering in Single Molecules Revealed by Ångstrom-Scale Tip-Enhanced Raman Imaging. [PDF]
de Campos Ferreira RC +9 more
europepmc +1 more source
Breaking Lock-ins to Enable a Green Pharmacy. [PDF]
Shalin A, Diamond ML, Wang Z.
europepmc +1 more source
Decarbonizing the Spanish Health System: A Qualitative Study on the Implementation of Environmental Regulations and Management Strategies in Health Institutions. [PDF]
Montes-Piña L +2 more
europepmc +1 more source

