Results 81 to 90 of about 219,271 (347)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Structural and Cohersion Funds: Theoretical and Statistical Aspects in Romania and EU

open access: yesTransylvanian Review of Administrative Sciences, 2011
The paper approaches structural and cohesion funds for the financial perspective 2007-2013. The article describes briefly the evolution of regional development policy, the financial allocations, the impact of EU funds within cohesion policy, legal and ...
Iulian Viorel BRAŞOVEANU   +3 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The EU Structural and Cohesion Funds: Solution or Smokescreen to Europe’s Regional Disparities? [PDF]

open access: yesRomanian Journal of European Affairs, 2004
The EU has long had a goal of ‘reducing economic and social disparities.’ Since the reforms to the European Structural Funds in 1988 the Commission has encouraged enhanced subnational actor participation in policy-making, although subsequent reforms in ...
Adrian Reilly
doaj  

Capacity of Phare and structural funds absorption: pre-accession versus post-accession [PDF]

open access: yes
The capacity of structural funds absorption is a priority for the member states of the European Union which accessed the EU in 2004 and 2007, but slowing rates of the absorption capacity of these funds were noticed in comparison to the absorption rates ...
Corina CACE   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Growing Significance of EU Institutions in Promotion of Inter-regional policies

open access: yesVestnik MGIMO-Universiteta, 2014
The article explores the variety of tools and vehicles applied within the EU to expand the prerogative of the regions of the EU member states. The author uses as an example the inter-regional policies in Belgium in respect of the Flemish Region and the ...
E. V. Ermakova
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Going NUTS: The Effect of EU Structural Funds on Regional Performance [PDF]

open access: yes
The European Union (EU) provides grants to disadvantaged regions of member states to allow them to catch up with the EU average. Under the Objective 1 scheme, NUTS2 regions with a GDP per capita level below 75% of the EU average qualify for structural ...
Maximilian Von Ehrlich   +3 more
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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