Results 251 to 260 of about 623,007 (310)

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

CRACK ONSET FROM A CIRCULAR CAVITY UNDER INTERNAL PRESSURE AND REMOTE BIAXIAL LOADING [PDF]

, 2018
A. Sapora, V. Mantič, I. García, P. Cornetti   +3 more
core  

Structural Integrity Enhancement and Sustainable Machining Process Optimization for Anti-Lock Braking System Hydraulic Valve Blocks. [PDF]

Materials (Basel)
Rusu AN, Dumitrascu DI, Dumitrascu AE.
europepmc   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

The kinesin-4 protein KIF27 forms a cytoskeletal scaffold at the transition zone to promote motile cilia structural integrity. [PDF]

Proc Natl Acad Sci U S A
Park H, Choi M, Zhang Y, Cheung HO, Makino S, Yoshikawa Y, Qi H, Liu Z, Lan G, Fu G, Wang Q, Guo SS, Liu P, Liu Z, Ti SC, Wang WJ, Li XD, Ni T, Hui CC, He M.   +19 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

4-Methylesculetin improves the growth performance of grass carp (<i>Ctenopharyngodon idella</i>) by enhancing the proliferation and structural integrity of the intestinal epithelium. [PDF]

Anim Nutr
Zhang J, Jiang W, Wu P, Liu Y, Ma Y, Shi H, Kuang S, Li S, Tang L, Zhou X, Feng L.   +10 more
europepmc   +1 more source

Enhancing structural integrity of magnesium with hydroxyapatite and tantalum reinforcement. [PDF]

Sci Rep
Ayalewu TS, Alemu AG, Wassie HM.
europepmc   +1 more source

The sequence and structural integrity of the SARS-CoV-2 Spike protein transmembrane domain is crucial for viral entry. [PDF]

Commun Biol
Ortiz-Mateu J, Belda D, Avilés-Alía AI, Alonso-Romero J, García-Murria MJ, Mingarro I, Geller R, Martinez-Gil L.   +7 more
europepmc   +1 more source

The structural integrity of human TFF1 under reducing conditions. [PDF]

Redox Biol
Elmaci DN, Hopping G, Hoffmann W, Muttenthaler M, Stein M.   +4 more
europepmc   +1 more source