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Structure and mechanism of kynureninase

Archives of Biochemistry and Biophysics, 2014
The kynurenine pathway is the major pathway of l-tryptophan catabolism in eukaryotes and some bacteria. In this pathway, kynureninase catalyzes the hydrolysis of l-kynurenine (in bacteria) or 3-hydroxy-l-kynurenine (in eukaryotes) to give anthranilic acid or 3-hydroxyanthranilic acid, respectively, and l-alanine.
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Transporter structure and mechanism

Trends in Neurosciences, 2004
During the past several decades, lac permease has assumed almost tutelary proportions as a model for cotransporters. This archetypical membrane protein now exerts its influence by the most dramatic means possible: its structure is solved. This article describes the configuration and implied transport mechanism of the bacterial lactose transporter and ...
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The causal structure of mechanisms

Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 2012
Recently, a number of philosophers of science have claimed that much explanation in the sciences, especially in the biomedical and social sciences, is mechanistic explanation. I argue the account of mechanistic explanation provided in this tradition has not been entirely satisfactory, as it has neglected to describe in complete detail the crucial ...
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Structural Mechanism of Muscle Contraction

Annual Review of Biochemistry, 1999
▪ Abstract  X-ray crystallography shows the myosin cross-bridge to exist in two conformations, the beginning and end of the “power stroke.” A long lever-arm undergoes a 60° to 70° rotation between the two states. This rotation is coupled with changes in the active site (OPEN to CLOSED) and phosphate release.
Geeves, M., Holmes, K.
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An introduction to the mechanics of tensegrity structures

Proceedings of the 40th IEEE Conference on Decision and Control (Cat. No.01CH37228), 2001
Tensegrity structures consist of strings (in tension) and bars (in compression). Strings are strong, light, and foldable, so tensegrity structures have the potential to be light but strong and deployable. Pulleys, NiTi wire, or other actuators to selectively tighten some strings on a tensegrity structure can be used to control its shape.
Robert E. Skelton   +4 more
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Hypergraph Products for Structural Mechanics

Civil-Comp Proceedings, 2012
In this paper Cartesian, direct and strong Cartesian product of hypergraphs are investigated. A new concept named the adjacency function is defined on hypergraphs. This definition leads to distinct adjacency and Laplacian matrices for a hypergraph and makes it possible to express it in an algebraic form.
Ali Kaveh, B. Alinejad
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Cysteine dioxygenase: structure and mechanism

Chemical Communications, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Joseph, CA, Maroney, MJ
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Structure and Mechanics of Starch Bread

Journal of Cereal Science, 1996
Abstract The mechanical properties of breads made of potato or wheat starch were measured in two successive compression/decompression cycles. From the shape of the stress–strain curves, the initial modulus and the critical stress and strain could be derived; the critical stress and strain are those at which the crumb structure starts to collapse. The
Keetels, C.J.A.M.   +4 more
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Stochastic Optimization for mechanical structures

Mathematical Methods of Operations Research, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Mechanizing structural induction.

2013
This thesis proposes improved methods for the automatic generation of proofs by structural induction in a formal system. The main application considered is proving properties of programs. The theorem-proving problem divides into two parts: (1) a formal system, and (2) proof generating methods.
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