Results 201 to 210 of about 5,320,256 (311)

A Low‐Cost, Handheld Optical Stiffness Sensor for Minimally Invasive Surgery

Advanced Robotics Research, EarlyView.
A novel handheld stiffness sensor is presented for real‐time tissue stiffness characterization. By simultaneously sensing contact force and tissue deformation, the device enables accurate stiffness quantification without requiring precise manual control. This approach offers a promising solution for intraoperative tumor detection and minimally invasive
Qianyu Ma, Ruxiang Jiang, Kaspar Althoefer, Nicolas Herzig, Hareesh Godaba   +4 more
wiley   +1 more source

Brain structural MRI marker for predicting conversion to Parkinson's disease in individuals with prodromal symptoms. [PDF]

Front Aging Neurosci
Park CH, Yoon U, Lee PH, Kim J, Lee SK, Shin NY.   +5 more
europepmc   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, EarlyView.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

A radiomics model predicts progression from mild cognitive impairment to alzheimer's disease using structural MRI. [PDF]

Sci Rep
Li Y, Yi P, Jin M, Li Y, Chen W.
europepmc   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

Altered Topology of Brain Structural Network in Patients With Migraine Without Aura: A Structural MRI Study. [PDF]

Eur J Pain
Cao ZM, Jia JN, Liu GY, Yang ZQ, Zhang JS, Shi AQ, Chen YC, Huo JW, Zhang YN, Liu N, Yan CQ, Wang J.   +11 more
europepmc   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Longitudinal structural MRI-based deep learning and radiomics features for predicting Alzheimer's disease progression. [PDF]

Alzheimers Res Ther
Aghajanian S, Mohammadifard F, Mohammadi I, Rajai Firouzabadi S, Baradaran Bagheri A, Moases Ghaffary E, Mirmosayyeb O.   +6 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Multimodal phenotypic classification of generalized anxiety and panic using structural MRI data and psychosocial factors: machine learning results from the German National Cohort (NAKO) study. [PDF]

Transl Psychiatry
Gutzeit J, Weiß M, Kuhn T, Klinger-König J, Streit F, Jockwitz C, Brandes B, Wright MN, Friedrich CM, Woeckel M, Mikolajczyk R, Keil T, Castell S, Betker P, Schlett CL, Bärnighausen TW, Bamberg F, Günther M, Hirsch JG, Pischon T, Niendorf T, Leitzmann MF, Bohmann P, Wirkner K, Krist L, Wang Y, Berger K, Walther S, Grabe HJ, Deckert J, Caspers S, Hein G, Erhardt-Lehmann A.   +32 more
europepmc   +1 more source