Results 101 to 110 of about 4,850,254 (305)
, 2018 Observations are inevitably contaminated with measurement uncertainty, which is a predominant source of uncertainty in some cases. In present practice probabilistic models are typically fitted to measurements without proper consideration of this ...
Sýkora, M., Rózsás, A.
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
RELIABILITY-BASED DESIGN OF COASTAL STRUCTURES [PDF]
, 1997 The objective of this paper is to introduce the application of reliability theory for conceptual design and evaluation of coastal structures. It is without the scope to discuss the validity and quality of the various design formulae available for coastal structures.
openaire +3 more sources
Reliability assessment of structural systems subject to deterioration over time
, 1997 A probabilistic procedure for the analysis of the current and future reliability of existing structural components and systems is developed: they are assumed subject to deterioration over time, due to the exposure to an aggressive environment as well as ...
CIAMPOLI, Marcello
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Structural Reliability of Existing Structures – Case Study
, 2014 reliability-based methodology for the assessment and evaluation of reinforced concrete (R/C) structural elements of concrete structures is presented herein. The results of the reliability analysis and assessment for R/C structural elements were verified by the results obtained through deterministic methods.
Z. Sakka +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
On the stress- and strain-based fatigue behavior of welded thick-walled nodular cast iron
Fracture and Structural IntegrityNodular cast iron (GJS) represents one of the most widely used materials for vehicle, energy and heavy machinery industry. Nevertheless, foundries struggling with the influence of local material defects in GJS like pores, shrinkages and dross often ...
Christoph Bleicher +3 more
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