Results 111 to 120 of about 4,318,402 (294)

Semi-Supervised Classification With Graph Structure Similarity and Extended Label Propagation

IEEE Access, 2019
Graph-based semi-supervised learning (GSSL) has attracted great attention over the past decade. However, there are still several open problems: (1) how to construct a graph that effectively represents the underlying structure of data and (2) how to ...
Junliang Ma, Nannan Wang, Bing Xiao
doaj   +1 more source

A relation based measure of semantic similarity for Gene Ontology annotations [PDF]

, 2008
This work has been supported by Microsoft Research Cambridge and the Irish Research Council for Science, Engineering and Technology.Background: Various measures of semantic similarity of terms in bio-ontologies such as the Gene Ontology (GO) have been ...
Gaudin, Benoit, Sheehan, B, Gaudin, B, Aaron Quigley, Quigley Aaron, Sheehan Brendan, Benoit Gaudin, Quigley, A ; https://orcid.org/, Dobson Simon, Sheehan, Brendan, Quigley, Aaron John, Dobson, Simon Andrew, Brendan Sheehan, Simon Dobson, Gaudin Benoit, Dobson, S   +15 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Two Phase Non-Rigid Multi-Modal Image Registration Using Weber Local Descriptor-Based Similarity Metrics and Normalized Mutual Information

Sensors, 2013
Non-rigid multi-modal image registration plays an important role in medical image processing and analysis. Existing image registration methods based on similarity metrics such as mutual information (MI) and sum of squared differences (SSD) cannot achieve
Feng Yang, Mingyue Ding, Xuming Zhang, Yi Wu, Jiani Hu   +4 more
doaj   +1 more source

Dissimilar sequence: similar structure of proteins

Bio-Algorithms and Med-Systems, 2016
AbstractSequence-to-structure relation is one of the major objects of the analysis of protein folding problem. The pair of two small proteins (domains) of similar structure (β-hairpin/α-helix/β-hairpin) generated by the chains of similar length (about 60 amino acids) with very low sequence similarity (15%) is the object of the comparable analysis of 3D
Mateusz Banach, Leszek Konieczny, Irena Roterman   +2 more
openaire   +3 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Determinant factors of structural similarity at the regional level: evidence from Portugal [PDF]

There is scant evidence on the determinant factors of structural similarity between geographical spaces; moreover, it has been produced considering only the national level. The present study provides evidence on this topic at the regional level, based on
Maria Paula Fontoura, Nuno Crespo
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Drivers of structural similarity

, 2018
The dataset contains a measure of structural similarity/convergence (pairwise Krugman specialization index) along with 54 potential determinants of structural ...
Beck, K (via Mendeley Data)
core   +1 more source