Results 121 to 130 of about 542,871 (298)
Can Neuroscience Help Predict Future Antisocial Behavior? [PDF]
, 2016 Part I of this Article reviews the tools currently available to predict antisocial behavior. Part II discusses legal precedent regarding the use of, and challenges to, various prediction methods.
Anderson, Nathaniel E. +3 more
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Toward a Better Future for this Generation and the Next... [PDF]
, 2012 The Oak Foundation commissioned Promundo-US to review and assess Oak's overall strategy in relation to its goal of engaging men and boys in the elimination of sexual abuse of children and comment more specifically on possible priorities and directions ...
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Memorie dislocate e biografie spezzate di Minori Stranieri Non Accompagnati
Archivio Antropologico MediterraneoThe article examines the violence and suffering experienced by unaccompanied foreign minors arriving by land in the cross-border area of Trieste. These are forms of structural violence, "layered" across space and time, starting with the causes of ...
Roberta Altin
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Eating your insides out: cultural, physical and institutionally-structured violence in the prison place [PDF]
This article explores three forms of violence in the prison place: physical, cultural and structural. The article starts with an overview of the nature and extent of 'everyday mundane' physical violence in the prison place, drawing upon but also ...
Scott, DG
core
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Taking Action on Racism and Structural Violence in Psychiatric Training and Clinical Practice. [PDF]
Can J Psychiatry, 2023 Jarvis GE +22 more
europepmc +1 more source