Results 121 to 130 of about 139,819 (304)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Transposition of Power: Law, Lawyers and Social Movements [PDF]

open access: yes, 2017
Various groups of people have been the victims of oppression throughout time and across national borders and cultures. Many forms of oppression continue to exist all over the world today, including in the United States. I have been particularly concerned
Diamond, Michael R.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

STRUCTURATION IN COMMUNICATION OF VEGETABLE FARMERS WITH MIDDLEMAN IN BATURITI DISTRICT TABANAN BALI

open access: yesE-Journal of Cultural Studies
This study aimed to uncover patterns of structuration in communication between vegetable growers and intermediaries in the Baturiti District. This study employs a critical communication methodology.
Renata Lusilaora Siringo Ringo   +3 more
doaj   +1 more source

The Patient as a construction and a non-participant member of a change-process. [PDF]

open access: yes
The contribution of this paper is a discussion about how the patient as a phenomenon is constructed and used by employees for different purposes, enabling and inhibiting change.
Beckerman, Carina
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Benefits of InterSite Pre-Processing and Clustering Methods in E-Commerce Domain [PDF]

open access: yes, 2005
This paper presents our preprocessing and clustering analysis on the clickstream dataset proposed for the ECMLPKDD 2005 Discovery Challenge. The main contributions of this article are double.
Chelcea, Sergiu Theodor   +4 more
core   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The ‘Asabiyya-Driven Structuration of Women’s Breast Cancer in the Arab Region [PDF]

open access: yesGlobal Media Journal: Canadian Edition, 2014
The Arab region witnesses more than 60% of reported breast cancer cases detected at a late stage, stage III or higher. Establishing a well-founded regional network ensures maximum impact in regards to the implementation and success of preventative and ...
Arwa Luqman
doaj  

The emergence of information systems: a communication-based theory [PDF]

open access: yes, 2010
An information system is more than just the information technology; it is the system that emerges from the complex interactions and relationships between the information technology and the organization.
Holten, Roland, Rosenkranz, Christoph
core   +1 more source

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