Results 51 to 60 of about 10,471,452 (238)

Modelling Flavour Release through Quantitative Structure Property Relationships (QSPR)

CHIMIA, 2001
The use of QSPR to explain the partition behaviour of flavour compounds in different matrices and to predict dynamic flavour release from certain food systems is described.
Andrew J. Taylor, Robert S.T. Linforth
doaj   +2 more sources

Synthesis, liquid crystalline behaviour and structure–property relationships of 1,3-bis(5-substituted-1,3,4-oxadiazol-2-yl)benzenes

Beilstein Journal of Organic Chemistry, 2020
Two series containing 1,3-bis(1,3,4-oxadiazol-2-yl)benzene as a rigid core (RC) and alkyl or perfluoroalkyl as terminal chains were synthesized and characterized. Liquid crystal properties of the synthesized compounds have been investigated by polarizing
Afef Mabrouki, Malek Fouzai, Armand Soldera, Abdelkader Kriaa, Ahmed Hedhli   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Structure-Mechanical Property Relationships in Engineering Polymers

CHIMIA, 2001
An overview is given of recent work in our laboratory aimed at exploring structure-mechanical property relationships in engineering polymers. This has involved both model systems and systems with direct relevance to practical industrial problems.
Christopher J.G. Plummer, Philippe Béguelin   +1 more
doaj  

Structure–Glass Transition Relationships in Non-Isocyanate Polyhydroxyurethanes

Molecules
The molecular dynamics, with an emphasis on the calorimetric and dynamic glass transitions, of non-isocyanate polyhydroxyurethanes (PHUs) produced by the equimolar polyaddition of polyether-based dicyclic carbonates (P-CCs) and various short diamines was
Konstantinos N. Raftopoulos, Izabela Łukaszewska, Sebastian Lalik, Paulina Zając, Artur Bukowczan, Edyta Hebda, Monika Marzec, Krzysztof Pielichowski   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Property and financial matters upon the breakdown of de facto relationships [PDF]

, 2014
Summary: Reforms introduced in 2009 to the Family Law Act 1975 (Cth) have meant that most samesex and opposite-sex de facto couples (in all states and territories except Western Australia) who end their relationships can now have their property and ...
Rachel Carson
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source