Results 221 to 230 of about 5,731,208 (381)

Phenothiazine drugs: structure-activity relationships explained by a conformation that mimics dopamine.

, 1975
Andrew P. Feinberg, Solomon H. Snyder
openalex   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Microbial Fermentation Affects the Structure-Activity Relationship of Bioactive Compounds in Ginseng and Its Applications in Fermentation Products: A Review. [PDF]

Foods
Bai J, Zhu Z, Luo W, Jang M, Pan B, Zhu Y, Zhang J, Zhao Y, Xiao X.   +8 more
europepmc   +1 more source

Inducers of erythroleukemic differentiation. Relationship of structure to activity among planar-polar compounds.

, 1978
Roberta C. Reuben, Pankaj Khanna, Yair Gazitt, Ronald Breslow, Richard A. Rifkind, P A Marks   +5 more
openalex   +1 more source

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source

Research Progress on the Structure-activity Relationship and Mechanism of Flavonoid Derivatives in the Treatment of Lung Cancer. [PDF]

Molecules
Yao J, Zhu F, Feng Y, Gu C, Wang T, Li X, Yang H, Hu X, Bonnet PA, Meng X.   +9 more
europepmc   +1 more source

α-ADRENOCEPTORS MEDIATING POSITIVE INOTROPIC EFFECTS ON THE VENTRICULAR MYOCARDIUM: SOME ASPECTS OF STRUCTURE-ACTIVITY RELATIONSHIP OF SYMPATHOMIMETIC AMINES

, 1976
M Endoh, Hans-Joachim Schümann, N. Krappitz, Barlo Hillen   +3 more
openalex   +1 more source

Inhibition of RNA polymerase and formyltetrahydrofolate synthetase activity by 6‐chloro‐8‐aza‐9‐cyclopentylpurine. Structure‐activity relationships [PDF]

, 1970
Raymond W. Ruddon, Cynthia H. Rainey, Morris S. Zedeck   +2 more
openalex   +1 more source

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

Exploring Substituted Dihydroxybenzenes as Urease Inhibitors through Structure-Activity Relationship Studies in Soil Incubations. [PDF]

Chempluschem
Nathanael JG, Kang H, Wille U.
europepmc   +1 more source