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Statistical Analysis of Structure-Activity Relationships
Toxicological Sciences, 1983The relationship between organic structure and biological activity (toxicity) is examined by statistically comparing concentration-response regression lines among structurally related compounds. Response data from acute toxicity tests are initially transformed to the logistic function while concentration data are transformed to the logarithm base 10 ...
K.L. Daniels +3 more
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[Structure-activity relationship of plant polysaccharides].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017Plant polysaccharides have a variety of biological activities and have become the focus of many fields such as the areas of medicine and food for the features of safety, high efficiency and low toxicity. The chemical structure of plant polysaccharides is
X. Tan, Xin Zhou, Huaguo Chen
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Structure-activity relationships of cytokinins
Phytochemistry, 1980(1990). Structure‐activity relationships of cytokinins. Critical Reviews in Plant Sciences: Vol. 9, No. 1, pp. 17-57.
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Structure-Activity Relationships in Coumermycins
1972Publisher Summary This chapter focuses on the structure–activity relationships in coumermycins. The naturally occurring coumermycins are produced in fermentation broths of several species of Streptomyces . Degradative studies at Bristol–Banyu Research Institute established the structures of coumermycins A 1 and A 2 .
Kenneth E. Price, John C. Godfrey
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Structure-Activity Relationships
1999Estrogens and antiestrogens are understood to exert their hormonal action after binding to the estrogen receptor (ER), a member of the nuclear receptor superfamily. Until recently, the knowledge of the shape of the full-length ER and the structure of the hormone-binding domain has been rather vague, due to the lack of cristallographie data. Information
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Structure-Activity Relationships in Glucocorticoids
1979Meaningful answers to the question of the relationship between glucocorticoid structure and activity have emerged. Structural change has predictable effects on susceptibility to the action of metabolizing enzymes, on receptor affinity, and on intrinsic activity. These effects are, in principle, amenable to mathematical modeling techniques.
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Antibacterial activities of flavonoids: structure-activity relationship and mechanism.
Current Medicinal Chemistry, 2014Flavonoids are well known as antibacterial agents against a wide range of pathogenic microorganism. With increasing prevalence of untreatable infections induced by antibiotic resistance bacteria, flavonoids have attracted much interest because of the ...
Yixi Xie +4 more
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Structure—Activity Relationships in the Actinomycins
1973Publisher Summary This chapter presents nomenclature of actinomycins (AMs) based on the peptide structure, which uses International Union of Pure and Applied Chemistry–International Union of Biochemistry (IUPAC–IUB) rules for naming peptide analogs.
Johannes Meienhofer, Eric Atherton
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Structure‐activity relationship study of anoplin
Journal of Peptide Science, 2004AbstractAnoplin is a decapeptide amide, GLLKRIKTLL‐NH2 derived from the venom sac of the solitary spider wasp, Anoplius samariensis. It is active against Gram‐positive and Gram‐negative bacteria and is not hemolytic towards human erythrocytes. The present paper reports a structure‐activity study of anoplin based on 37 analogues including an Ala‐scan, C‐
Ifrah, D. +3 more
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Covalency competition dominates the water oxidation structure–activity relationship on spinel oxides
Nature Catalysis, 2020Yuanmiao Sun +13 more
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