Results 151 to 160 of about 33,351,014 (255)

Novel Phosphodiesterase‑2 Inhibitors Discovered via Structure-Based Virtual Screening Targeting the Allosteric GAF‑B Domain. [PDF]

ACS Med Chem Lett
Adeniran C, Myratgeldiyev G, Zheng F, Zhan CG.   +3 more
europepmc   +1 more source

Push the Limits: Human‐Like Multimodal Extreme Embodied Intelligence for Autonomous Racing

Advanced Robotics Research, EarlyView.
Autonomous racing tests embodied intelligence under extreme control limits of speed, actuation, and decision‐making. Inspired by human multimodality, we present Apex, an embodied agent deployed on a super‐formula racing car at Yas Marina. Integrating physics‐informed perception, multimodal learning, and tasking, Apex cuts lap times by 15% and achieves ...
Yanxin Zhou, Baichuan Lou, Wenhui Huang, Binbin Hu, Haohan Yang, Haochen Liu, Xiangkun He, Chee Kiong Ong, Yiran Zhang, Tianchu Su, Bolin Zhao, Xiaoyu Mo, Holden King Ho Li, Chen Lv   +13 more
wiley   +1 more source

Artificial Intelligence- and Machine Learning-Assisted Structure-Based Virtual Screening of Compounds That Target 15PGDH. [PDF]

Pharmaceutics
Ahmad SS, Choi I.
europepmc   +1 more source

Real‐Time Holographic Feedback via Mixed Reality Sensorized Laryngoscope Training System Enhances Pediatric Intubation Training

Advanced Robotics Research, EarlyView.
We proposed a Mixed Reality Sensorized Laryngoscope Training System to provide real‐time holographic torque feedback during pediatric endotracheal intubation simulation. Visualization formats are evaluated to reduce tracking error and visual demand.
Jiaqi Li, Ryman Hashem, Ningzhe Hou, Perla Maiolino, Louis Halamek, Liang He   +5 more
wiley   +1 more source

V-SYNTHES2-the next generation tool for structure-based virtual screening of giga-scale chemical spaces. [PDF]

NPJ Drug Discov
Nazarova AL, Sadybekov AV, Sadybekov AA, Protopopov M, Radchenko DS, Moroz YS, Tarkhanova OO, Katritch V.   +7 more
europepmc   +1 more source

A Low‐Cost, Handheld Optical Stiffness Sensor for Minimally Invasive Surgery

Advanced Robotics Research, EarlyView.
A novel handheld stiffness sensor is presented for real‐time tissue stiffness characterization. By simultaneously sensing contact force and tissue deformation, the device enables accurate stiffness quantification without requiring precise manual control. This approach offers a promising solution for intraoperative tumor detection and minimally invasive
Qianyu Ma, Ruxiang Jiang, Kaspar Althoefer, Nicolas Herzig, Hareesh Godaba   +4 more
wiley   +1 more source

SurroDock: A Deep Learning Surrogate for Accelerated Pre-Docking Ligand Prioritization in Structure-Based Virtual Screening. [PDF]

Int J Mol Sci
Choi J.
europepmc   +1 more source

Continuum Robots in Surgery: From Engineering Design to Clinical Practice

Advanced Robotics Research, EarlyView.
The hyper‐redundant nature of continuum robot structures enables near‐infinite degrees of freedom leading to immense potential for medical applications. This review provides a historical background of continuum robots and novel ideas shaping their progress to current structural design, sensing technology, modeling techniques, and control methods.
Griffin Smith, Kaitlyn Clancy, Siwen Xie, Xiaochen Li, Sarah Khalife, Benjamin van der Woerd, Onaizah Onaizah   +6 more
wiley   +1 more source

Flexible Sensors for Robotics Tactile Perception: A Review

Advanced Robotics Research, EarlyView.
Flexible tactile sensing for robotics is reviewed through four interconnected dimensions. Physical mechanisms include piezoresistive, capacitive, piezoelectric, triboelectric, iontronic, and optical sensing. Structural design includes bioinspired, defect‐based, and MEMS‐based tactile systems.
Yu Song, Ying Chen, Yihao Chen, Xue Feng
wiley   +1 more source

Identification of New Putative Autotaxin Inhibitors via Structure-Based Virtual Screening and Evaluation of Their Antiproliferative Properties Against Ovarian and Breast Cancer Cells. [PDF]

ChemMedChem
Boccarelli A, Coricello A, Ambrosio FA, Leo V, Mirabile S, Gitto R, de Candia M, Catto M, Ortuso F, Altomare CD, Alcaro S.   +10 more
europepmc   +1 more source