Results 81 to 90 of about 38,529,781 (313)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A low-cost digital 3D insect scanner

Information Processing in Agriculture
Collections of biological specimens are essential in entomology laboratories for scientific knowledge and the characterization of natural varieties. It is vital to liberate useful information from physical collections by digitizing specimens, allowing ...
Thanh-Nghi Doan, Chuong V. Nguyen
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Two-pass hexagonal algorithm with improved hashtable structure for motion estimation

, 2005
This paper presents an improved two-pass hexagonal (TPA) algorithm constituted by linear hashtable motion estimation algorithm (LHMEA) and hexagonal search (HEXBS) for motion estimation.
Megson, G.M., Wu, Y.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A semantic feature for human motion retrieval [PDF]

, 2013
With the explosive growth of motion capture data, it becomes very imperative in animation production to have an efficient search engine to retrieve motions from large motion repository.
Zhuang, Yueting, Qi, T., Jianjun Zhang, Tian Qi, Zhang, Jian J., Feng, Yinfu, Yinfu Feng, Xiaosong Yang, Xiao, J., Yueting Zhuang, Yang, Xiaosong, Jun Xiao   +11 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Motion computation and visual orientation in flies

, 1993
Egelhaaf M, Borst A. Motion computation and visual orientation in flies. Comparative Biochemistry and Physiology, A: Comparative Physiology. 1993;104(4):659-673.Visual orientation greatly relies on the evaluation of the motion patterns received by the ...
Egelhaaf, M., Borst, Alexander, Egelhaaf, Martin ; https://orcid.org/, Borst, A.   +3 more
core   +1 more source

Reliable camera motion estimation from compressed MPEG videos using machine learning approach [PDF]

, 2013
As an important feature in characterizing video content, camera motion has been widely applied in various multimedia and computer vision applications. A novel method for fast and reliable estimation of camera motion from MPEG videos is proposed, using ...
Wang, Yubin, Wang, Zheng, Ren, Jinchang, Sun, Meijun, Jiang, Jianmin   +4 more
core   +1 more source