Results 181 to 190 of about 22,404,851 (343)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Structured ceramic surfaces by preceramic polymer demixing processes

, 2013
Alexandra Laskowsky, Ann-Karolin Schuldt, Michael Woiton, Madeleine Heyder, Edda Stern, Michael Scheffler   +5 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Reply to: Neutron diffraction evidence of the 3-dimensional structure of Ba₂MnTeO₆ and misidentification of the triangular layers within the face-centred cubic lattice. [PDF]

Sci Rep
Khatua J, Arh T, Mishra SB, Luetkens H, Zorko A, Sana B, Rao MSR, Nanda BRK, Khuntia P.   +8 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Diverse database and machine learning model to narrow the generalization gap in RNA structure prediction. [PDF]

Sci Adv
de Lajarte AA, Taillades YJMD, Aruda J, Bongrand P, Wightman FF, Salazar D, Allan MF, Kalicki C, L'Esperance-Kerckhoff C, Kashi A, Jossinet F, Rouskin S.   +11 more
europepmc   +1 more source

Faster and Still Safe: Combining Screening Techniques and Structured Dictionaries to Accelerate the Lasso

, 2018
Cássio F. Dantas, Rémi Gribonval
openalex   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Round robin on structure analysis from 3D electron diffraction data. [PDF]

IUCrJ
Gemmi M, Palatinus L, Boullay P, Abrahams JP, Ben Meriem A, Cordero-Oyonarte E, Emerson Agbemeh V, Chintakindi H, Faye Diouf MD, Filipcik P, Gemmrich Hernandéz L, van Genderen E, Hadermann J, Hajizadeh A, Jeriga B, Kolb U, Matinyan S, Passuti S, Santucci M, Suresh A, Pérez O, Tai CW, Vypritskaia A, Wang L, Xu H, Zou X.   +25 more
europepmc   +1 more source

Evolution of defect structure of grossly nonstoichiometric Ca_1−xR_xF_2+xcrystals (R³⁺= La, Nd, Dy, Ho, Yb) [PDF]

, 1996
N. B. Grigorieva, L. P. Otroschenko, B. Maximov, Б. П. Соболев, V. I. Simonov   +4 more
openalex   +1 more source