Search for Origins of Anti-CRISPR Proteins by Structure Comparison. [PDF]
Sahakyan H, Makarova KS, Koonin EV.
europepmc +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Random subcubes as a toy model for constraint satisfaction problems
We present an exactly solvable random-subcube model inspired by the structure of hard constraint satisfaction and optimization problems. Our model reproduces the structure of the solution space of the random k-satisfiability and k-coloring problems, and ...
A. Barg +39 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Chemical Structure Comparison via Scanning Electron Microscopy of Spent Commercial Nickel-Metal Hydride Batteries. [PDF]
Walther T.
europepmc +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Structure comparison and evenness test of biological communities: Several platform-independent computational tools [PDF]
The comparison of structural difference between biological communities and the evenness or diversity test of biological communities are always the focus in community studies.
WenJun Zhang
doaj
Specificity of Monoterpene Interactions with Insect Octopamine and Tyramine Receptors: Insights from in Silico Sequence and Structure Comparison. [PDF]
Ocampo AB +4 more
europepmc +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
An empirical study on performance comparisons of different types of DevOps team formations
IntroductionDespite all the efforts to successfully implement DevOps practices, principles, and cultural change, there is still a lack of understanding on how DevOps team structure formation and performance differences are related.
Halil Ergun Korkmaz, Mehmet Nafiz Aydin
doaj +1 more source

