Results 91 to 100 of about 2,175,997 (287)

Proteção do conhecimento e inovação: as amarras explícitas em uma universidade do Paraná │ Knowledge protection and innovation: the explicit ties in a university of Paraná, Brazil

Liinc em Revista, 2014
RESUMO O presente estudo procurou identificar o cenário para a proteção do conhecimento e inovação no meio acadêmico, bem como as dificuldades encontradas pelos pesquisadores no processo de patenteamento.
Adriana Aguillera Gonçalves, Maria Inês Tomaél   +1 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Etude des interactions mécaniques entre un bloc en mouvement et le milieu extérieur

Sciences, Eaux & Territoires, 2003
Les instabilités rocheuses figurent parmi les aléas rencontrés fréquemment en zone de montagne. Afin de réduire le risque associé, la stratégie dite passive vise à mettre en place des techniques de protection qui permettent de contrôler la trajectoire ...
F. NICOT
doaj  

The Philippines: Shadow WTO Agricultural Domestic Support Notifications [PDF]

"The objective of this paper is to review the agricultural trade and domestic policies of the Philippines and to provide an assessment of the types and levels of domestic support relative to the rules of the World Trade Organization (WTO).
Cororaton, Caesar B.
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Protection de structures soumises à des sollicitations dynamiques à l’aide d’un absorbeur non-linéaire [PDF]

, 2021
Au cours de la dernière décennie, il a été démontré que des absorbeurs dits non-linéaires peuvent apporter des bénéfices importants en termes d'atténuation de vibrations et de tenue aux chocs, le tout pour une masse ajoutée très faible. A la différence des absorbeurs déjà existants dans l'industrie, ces dispositifs font intervenir une dynamique ...
openaire  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Diversité floristique des forêts communautaires de la préfecture de Dankpen au Togo

Revue Marocaine des Sciences Agronomiques et Vétérinaires, 2022
Cette étude est une contribution à la gestion des forêts communautaire (FC) dans la préfecture de Dankpen: FC de Namab (FCNam), Nassibik (FCNas) et Yakandjido (FCY).
Wouyo ATAKPAMA, Hodabalo EGBELOU, Fousseni FOLEGA, Chakourou AFO, Komlan BATAWILA, Koffi AKPAGANA   +5 more
doaj  

Algumas reflexões sobre o sistema de garantia de direitos Some reflection on the system of guarantee of rights

Serviço Social & Sociedade, 2012
Para realizar uma reflexão sobre o sistema de garantia de direitos, este artigo toma por ponto de partida pontuar o processo secular de universalização dos direitos humanos e como essa questão foi se colocando historicamente à sociedade brasileira. Trata
Myrian Veras Baptista
doaj   +1 more source