Results 101 to 110 of about 6,089,716 (332)

Structure formation in the Lemaitre-Tolman model

open access: yes, 2001
Structure formation within the Lemaitre-Tolman model is investigated in a general manner. We seek models such that the initial density perturbation within a homogeneous background has a smaller mass than the structure into which it will develop, and the ...
A. Barnes   +14 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Modified-Source Gravity and Cosmological Structure Formation

open access: yes, 2006
One way to account for the acceleration of the universe is to modify general relativity, rather than introducing dark energy. Typically, such modifications introduce new degrees of freedom.
Adams A Arkani-Hamed N Dubovsky S Nicolis A Rattazzi R   +36 more
core   +1 more source

Cosmological Structure Formation [PDF]

open access: yes, 2017
31 pages, 6 figures, invited lecture at Philosophy of Cosmology conference in Tenerife, September 2014, for proceedings to be published by Cambridge University Press; lecture slides are at https://goo.gl/zr1c6B, video is at https://goo.gl ...
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The Jewish 'ghetto': formation and spatial structure [PDF]

open access: yes, 2001
Research into patterns of immigrant settlement has consistently indicated that certain areas of cities are prone to settlement by immigrant groups. This paper proposes that immigrant settlement of such areas may have a particular spacial pattern.
Penn, A, Vaughan, L
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Reshaping our understanding on structure formation with the quantum nature of the dark matter

open access: hybrid, 2023
C. R. Argüelles   +5 more
openalex   +1 more source

Gravitational Structure Formation

open access: yes, 2005
Procedings of the conference "Few-Body Problem: Theory and Computer Simulations A Workshop in celebration of the 60th Birthday of Professor Mauri Valtonen.
Labini, Francesco Sylos   +1 more
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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