Results 101 to 110 of about 32,189,684 (346)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Dark Matter Haloes and Subhaloes

open access: yesGalaxies, 2019
The development of methods and algorithms to solve the N-body problem for classical, collisionless, non-relativistic particles has made it possible to follow the growth and evolution of cosmic dark matter structures over most of the universe’s ...
Jesús Zavala, Carlos S. Frenk
doaj   +1 more source

Semisolid structure formation and semisolid casting

open access: yes, 2005
Semisolid metal forming has now been accepted as a viable technology for production of components with complex shape and high integrity. The advantages of semisolid metal forming can only be achieved when the feedstock material has a non-dendritic ...
Wang, Hao
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Primordial black hole formation during slow-reheating: a review

open access: yesFrontiers in Astronomy and Space Sciences
In this paper we review the possible mechanisms for the production of primordial black holes (PBHs) during a slow-reheating period in which the energy transfer of the inflaton field to standard model particles becomes effective at slow temperatures ...
Luis E. Padilla   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Structure, lipid scrambling activity and role in autophagosome formation of ATG9A

open access: yesNature Structural & Molecular Biology, 2020
De novo formation of the double-membrane compartment autophagosome is seeded by small vesicles carrying membrane protein autophagy-related 9 (ATG9), the function of which remains unknown.
Shintaro Maeda   +9 more
semanticscholar   +1 more source

Surface dipole formation and electronic structure evolution on β -Ga2O3

open access: yes
The surface electronic structure of Ga2O3 critically influences its metal/Ga2O3 contact and semiconductor/Ga2O3 interface property, as well as the overall device performance.
Zhou, Jie   +11 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Group formation and social evolution: a computational model

open access: yes, 2008
The tendency to organise into groups is a fundamental property of human nature. Despite this, many models of social network evolution consider the emergence of community structure as a side effect of other processes, rather than as a mechanism driving ...
Nicholas Geard   +3 more
core   +1 more source

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