Results 41 to 50 of about 515,312 (263)

A Review of the Low-Carbon Transformation Path of Buildings Driven by Renewable Energy: Challenges and Optimization of Energy-Efficient Utilization

Buildings
Under the backdrop of the “dual carbon” strategy, leveraging renewable energy to promote low-carbon renovations of existing buildings has become an important path for the construction industry to achieve sustainable development.
Ping Jiang, Kebo He, Na Li, Lifeng Xu, Haihua Zhan   +4 more
doaj   +1 more source

Local Translation in Growth Cones and Presynapses, Two Axonal Compartments for Local Neuronal Functions

Biomolecules, 2020
During neural development, growth cones, very motile compartments of tips of axons, lead axonal extension to the correct targets. Subsequently, presynapses, another axonal compartment with vigorous trafficking of synaptic vesicles, emerge to form ...
Yukio Sasaki
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

USING THE PRINCIPLES OF TACTICAL URBANISM IN THE RENOVATION OF THE ESPLANADE IN THE CITY OF PERM

Архитектон, 2022
The article presents some economic and analytical prerequisites and substantiation of the planning concept for the Explanada territory of Perm. Specific design solutions for the renovation of the city esplanade are considered and substantiated in more ...
Shchipalkin Victor P., Shchipalkina Tatyana V., Kuryakova Natalia B., Raizikh Ekaterina V.   +3 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Rewriting and city structure

Festival dell'Architettura Magazine, 2021
Re-taking from literary practices the attitude of critically reworking formal characteristics belonging to something previous, rewriting offers itself as a possible technique for transforming parts of the city. This approach makes it possible to prevent mimetic results, highlighting conversely the substantial texture of the city, selecting its ...
openaire   +2 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Influence of Wrap-Around Facing Types on the Seismic Response of Reinforced Loess Slopes: A Comparative Study of Two Seismic Waves

Buildings
To promote the application of wrap-around reinforced soil structures in high-intensity seismic regions, this study systematically investigated the influence of different wrap-around facing types on the seismic performance of reinforced loess slopes ...
Zhicheng Zhao, Xin Huang, Xiaoguang Cai, Sihan Li, Honglu Xu, Jiayu Feng, Weixin Wang   +6 more
doaj   +1 more source

The origin and development of Garden cities: An overview [PDF]

Zbornik Radova: Geografski Fakultet Univerziteta u Beogradu, 2019
An overview of Garden City development as well as its significance in urban planning, are given in this paper. The Garden City idea, which had a major role in the 20th century urbanism, was born in London.
Gatarić Dragica, Belij Marija, Đerčan Bojan, Filipović Dejan   +3 more
doaj