Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Enzyme-Responsive Cyclic Gapmer Antisense Oligonucleotides via Thymidine <i>C</i>5-<i>C</i>5 Cross-Linking within the Gap Region Using a Galactosylated Branched Self-Immolative Linker. [PDF]
Miyaji K, Habu N, Seio K.
europepmc +1 more source
Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays
An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen +9 more
wiley +1 more source
Interface States in Space-Time Photonic Crystals: Topological Origin, Propagation, and Amplification. [PDF]
Caballero A, Allard TF, Huidobro PA.
europepmc +1 more source
First‐principles calculations reveal that monolayer In2O${\rm In}_2{\rm O}$ hosts type‐II Dirac fermions near the Fermi level, which split into Weyl points under spin‐orbit coupling. The material exhibits negative and giant magnetoresistance, a pronounced spin Hall effect, and phonon‐mediated superconductivity at 1.5 K, establishing it as a unique ...
Qing‐Bo Liu +6 more
wiley +1 more source
Whole body analysis of functional communities and topological features of gait with different speeds in Parkinson's disease. [PDF]
Saegner K +7 more
europepmc +1 more source
A hierarchically structured Fe‐BTC‐PMA immobilized 3D‐printed platform is engineered as a robust artificial enzyme for colorimetric glucose sensing. The hybrid architecture efficiently activates H2O2 to drive TMB oxidation. This integrated system enables sensitive, reusable, and scalable detection with enhanced catalytic stability and analytical ...
Paramita Koley +10 more
wiley +1 more source
A Negatively Curved Pyrene-Fused Azaacene. [PDF]
Carini M +3 more
europepmc +1 more source
ABSTRACT Large‐ion (K, Na) battery systems mitigate uneven global lithium distribution, while their ability to attain recharge time shorter than refueling would remove the final barrier for secondary batteries to replace petroleum vehicles. However, their large‐ion chemistry makes ultra‐fast charging an even significant challenge.
Shukai Ding +12 more
wiley +1 more source
Subgingival microbiota composition is associated with brain health in the general population-the PAROMIND study. [PDF]
Petersen M +16 more
europepmc +1 more source

